Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Chromosomes
  • Tools
  • Genetic and Physical SNP Maps
  • SNP500Cancer
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

The Recurrent Chromosome Aberrations in Cancer Database Searcher
  • Brief instructions for searching the database:
    • You must choose one or both of the following two fields: Structural Aberrations and Numerical Aberrations.
    • If you choose Structural Aberrations, you must select at least one of the following fields: Breakpoint, Topography, Morphology, or Gene.
    • If you choose Numerical Aberrations, you must select at least one of the following fields: Chromosome, Topography, Morphology.
    • You may select only one item in each pulldown menu
    • Press Retrieve.
  • A successful search returns a table, with the following headings and entries:
    • Breakpoint, with each entry linked to the OMIM Gene Map (this column is returned only for structural aberrations)
    • Abnormality
    • Morphology, with each entry linked to a similar table that describes all abnormalities with this morphology.
    • Topography, with each entry linked to a similar table that describes all abnormalities at this topography
    • Number of cases, hyperlinked to the list of applicable cases
    • Genes

Aberration type:
Aberration type:




Expand Topography List:

Expand Morphology List:

Expand Gene List:




[Full Text]

Balanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
1p21 t(1;8)(p21;q24) Multiple myeloma    
1p21 t(X;1)(p21;p21) Follicular lymphoma    

Unbalanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
1p21 add(1)(p21) Acute myeloid leukemia, NOS    
1p21 add(1)(p21) Diffuse large B-cell lymphoma    
1p21 add(1)(p21) Mesothelioma Pleura  
1p21 add(1)(p21) Multiple myeloma    
1p21 del(1)(p11p21) Multiple myeloma    
1p21 del(1)(p12p21) Multiple myeloma    
1p21 del(1)(p21) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
1p21 del(1)(p21) Acute myeloid leukemia, NOS    
1p21 del(1)(p21) Adenocarcinoma Ovary  
1p21 del(1)(p21) Adenocarcinoma Breast  
1p21 del(1)(p21) Adenocarcinoma Kidney  
1p21 del(1)(p21) Adenocarcinoma Uterus, corpus  
1p21 del(1)(p21) Adenocarcinoma Pancreas  
1p21 del(1)(p21) Chronic lymphocytic leukemia    
1p21 del(1)(p21) Combined germ cell tumors Testis  
1p21 del(1)(p21) Diffuse large B-cell lymphoma    
1p21 del(1)(p21) Ewing sarcoma Skeleton  
1p21 del(1)(p21) Hodgkin disease, nodular sclerosis    
1p21 del(1)(p21) Malignant melanoma Eye  
1p21 del(1)(p21) Malignant peripheral nerve sheath tumor/Triton Soft tissue  
1p21 del(1)(p21) Mantle cell lymphoma    
1p21 del(1)(p21) Meningioma Brain  
1p21 del(1)(p21) Mesothelioma Pleura  
1p21 del(1)(p21) Multiple myeloma   16   
1p21 del(1)(p21) Refractory anemia with excess of blasts (FAB)    
1p21 del(1)(p21) Teratoma (mature and immature) Testis  
1p21 del(1)(p21p22) Multiple myeloma    
1p21 del(1)(p21p31) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
1p21 del(1)(p21p31) Mantle cell lymphoma    
1p21 del(1)(p21p31) Multiple myeloma   17   
1p21 del(1)(p21p34) Adenocarcinoma Oesophagus  
1p21 del(1)(p21p34) Multiple myeloma    
1p21 del(1)(p21p36) Multiple myeloma