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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

The Recurrent Chromosome Aberrations in Cancer Database Searcher
  • Brief instructions for searching the database:
    • You must choose one or both of the following two fields: Structural Aberrations and Numerical Aberrations.
    • If you choose Structural Aberrations, you must select at least one of the following fields: Breakpoint, Topography, Morphology, or Gene.
    • If you choose Numerical Aberrations, you must select at least one of the following fields: Chromosome, Topography, Morphology.
    • You may select only one item in each pulldown menu
    • Press Retrieve.
  • A successful search returns a table, with the following headings and entries:
    • Breakpoint, with each entry linked to the OMIM Gene Map (this column is returned only for structural aberrations)
    • Abnormality
    • Morphology, with each entry linked to a similar table that describes all abnormalities with this morphology.
    • Topography, with each entry linked to a similar table that describes all abnormalities at this topography
    • Number of cases, hyperlinked to the list of applicable cases
    • Genes

Aberration type:
Aberration type:




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[Full Text]

Balanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
19p13 inv(19)(p13q13) Astrocytoma, grade III-IV/Glioblastoma Brain  
19p13 inv(19)(p13q13) Hairy cell leukemia    
19p13 t(11;19)(q13;p13) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
19p13 t(11;19)(q21;p13) Mucoepidermoid carcinoma Salivary gland CRTC1/MAML2
19p13 t(11;19)(q23;p13) Acute erythroleukemia (FAB type M6)   H2AFX/WDR18,WDR18/H2AFX
19p13 t(11;19)(q23;p13) Acute lymphoblastic leukemia/lymphoblastic lymphoma   159  KMT2A/ELL,KMT2A/MLLT1,KMT2A+
19p13 t(11;19)(q23;p13) Acute monoblastic leukemia (FAB type M5)   28  KMT2A/ELL,KMT2A/MLLT1,KMT2A/MYO1F
19p13 t(11;19)(q23;p13) Acute monoblastic leukemia with differentiation (FAB type M5b)   19  KMT2A/ELL,KMT2A/MLLT1,KMT2A/SUGP2
19p13 t(11;19)(q23;p13) Acute monoblastic leukemia without differentiation (FAB type M5a)   28  KMT2A/MLLT1,KMT2A+
19p13 t(11;19)(q23;p13) Acute myeloblastic leukemia with maturation (FAB type M2)   25  KMT2A/ELL,KMT2A/MLLT1,KMT2A+
19p13 t(11;19)(q23;p13) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   KMT2A/MLLT1,KMT2A+
19p13 t(11;19)(q23;p13) Acute myeloblastic leukemia without maturation (FAB type M1)   23  KMT2A+
19p13 t(11;19)(q23;p13) Acute myeloid leukemia, NOS   48  KMT2A/ELL,KMT2A/MLLT1,KMT2A/MYO1F,KMT2A/SH3GL1,KMT2A/VAV1,KMT2A+
19p13 t(11;19)(q23;p13) Acute myelomonocytic leukemia (FAB type M4)   43  KMT2A/ELL,KMT2A/MLLT1,KMT2A+
19p13 t(11;19)(q23;p13) Acute undifferentiated leukemia   KMT2A+
19p13 t(11;19)(q23;p13) Bilineage or biphenotypic leukemia   17  KMT2A/ELL,KMT2A/MLLT1
19p13 t(11;19)(q23;p13) Chronic myeloid leukemia, aberrant translocation    
19p13 t(11;19)(q23;p13) Chronic myeloid leukemia, t(9;22)   KMT2A+
19p13 t(11;19)(q23;p13) Chronic myelomonocytic leukemia   KMT2A/ELL,KMT2A+
19p13 t(11;19)(q23;p13) Dendritic cell neoplasm   KMT2A/MLLT1
19p13 t(11;19)(q23;p13) Myelodysplastic syndrome, NOS   KMT2A/ELL,KMT2A+
19p13 t(12;19)(p13;p13) Acute lymphoblastic leukemia/lymphoblastic lymphoma   NOP2/TCF3,PLK5/ATN1,TCF3/ZNF384,TCF3+
19p13 t(12;19)(p13;p13) Bilineage or biphenotypic leukemia    
19p13 t(12;19)(q13;p13) Multiple myeloma    
19p13 t(13;19)(q14;p13) Chronic lymphocytic leukemia    
19p13 t(14;19)(q32;p13) Acute lymphoblastic leukemia/lymphoblastic lymphoma   12  IGH/EPOR
19p13 t(15;19)(q13;p13) Undifferentiated carcinoma Larynx  
19p13 t(17;19)(q21;p13) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
19p13 t(17;19)(q22;p13) Acute lymphoblastic leukemia/lymphoblastic lymphoma   12  TCF3/HLF
19p13 t(19;22)(p13;q11) Acute myeloid leukemia, NOS    
19p13 t(19;22)(p13;q11) Chronic myeloid leukemia, aberrant translocation    
19p13 t(1;19)(q12;p13) Malignant melanoma Skin  
19p13 t(1;19)(q21;p13) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
19p13 t(1;19)(q21;p13) Meningioma Brain  
19p13 t(1;19)(q22;p13) Acute lymphoblastic leukemia/lymphoblastic lymphoma   DAZAP1/MEF2D,MEF2D/DAZAP1
19p13 t(1;19)(q23;p13) Acute lymphoblastic leukemia/lymphoblastic lymphoma   175  TCF3/PBX1,TCF3+
19p13 t(1;19)(q23;p13) Burkitt lymphoma/leukemia   TCF3/PBX1
19p13 t(1;19)(q23;p13) Follicular lymphoma    
19p13 t(1;19)(q32;p13) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
19p13 t(1;19;11)(p36;p13;q23) Acute monoblastic leukemia (FAB type M5)   KMT2A/ELL
19p13 t(3;19)(p21;p13) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
19p13 t(7;19)(q21;p13) Chronic myeloid leukemia, aberrant translocation    
19p13 t(9;22;19)(q34;q11;p13) Chronic myeloid leukemia, aberrant translocation   11  BCR/ABL1
19p13 t(9;22;19;10)(q34;q11;p13;q22) Chronic myeloid leukemia, aberrant translocation    
19p13 tas(19;20)(p13;q13) Giant cell tumor of bone Skeleton  

Unbalanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
19p13 add(19)(p13) Acute erythroleukemia (FAB type M6)   13   
19p13 add(19)(p13) Acute lymphoblastic leukemia/lymphoblastic lymphoma   62   
19p13 add(19)(p13) Acute megakaryoblastic leukemia (FAB type M7)   11   
19p13 add(19)(p13) Acute monoblastic leukemia (FAB type M5)    
19p13 add(19)(p13) Acute myeloblastic leukemia with maturation (FAB type M2)    
19p13 add(19)(p13) Acute myeloblastic leukemia without maturation (FAB type M1)    
19p13 add(19)(p13) Acute myeloid leukemia, NOS   34   
19p13 add(19)(p13) Acute myelomonocytic leukemia (FAB type M4)    
19p13 add(19)(p13) Adenocarcinoma Prostate  
19p13 add(19)(p13) Adenocarcinoma Lung  
19p13 add(19)(p13) Adenocarcinoma Pancreas  
19p13 add(19)(p13) Adenocarcinoma Uterus, corpus  
19p13 add(19)(p13) Adenocarcinoma Gallbladder/Biliary system  
19p13 add(19)(p13) Adenocarcinoma Large intestine  
19p13 add(19)(p13) Adenocarcinoma Kidney  
19p13 add(19)(p13) Adenocarcinoma Breast  
19p13 add(19)(p13) Adenocarcinoma Ovary 29   
19p13 add(19)(p13) Adult T-cell lymphoma/leukemia (HTLV-1+)    
19p13 add(19)(p13) Alveolar rhabdomyosarcoma Soft tissue  
19p13 add(19)(p13) Anaplastic large cell lymphoma, systemic type    
19p13 add(19)(p13) Angioimmunoblastic T-cell lymphoma    
19p13 add(19)(p13) Astrocytoma, grade III-IV/Glioblastoma Brain  
19p13 add(19)(p13) B-prolymphocytic leukemia    
19p13 add(19)(p13) Bilineage or biphenotypic leukemia    
19p13 add(19)(p13) Carcinoma, NOS Breast  
19p13 add(19)(p13) Chondrosarcoma, NOS Skeleton  
19p13 add(19)(p13) Chondrosarcoma, dedifferentiated Skeleton  
19p13 add(19)(p13) Chronic lymphocytic leukemia    
19p13 add(19)(p13) Chronic myeloid leukemia, aberrant translocation    
19p13 add(19)(p13) Chronic myeloid leukemia, t(9;22)    
19p13 add(19)(p13) Combined germ cell tumors Testis  
19p13 add(19)(p13) Diffuse large B-cell lymphoma Testis  
19p13 add(19)(p13) Diffuse large B-cell lymphoma   25   
19p13 add(19)(p13) Endometrial stromal sarcoma Uterus, corpus  
19p13 add(19)(p13) Ewing sarcoma Skeleton  
19p13 add(19)(p13) Follicular lymphoma    
19p13 add(19)(p13) Hodgkin disease, NOS    
19p13 add(19)(p13) Hodgkin disease, mixed cellularity    
19p13 add(19)(p13) Hodgkin disease, nodular sclerosis    
19p13 add(19)(p13) Intravascular large B-cell lymphoma    
19p13 add(19)(p13) Leiomyosarcoma Soft tissue  
19p13 add(19)(p13) Liposarcoma, dedifferentiated Soft tissue  
19p13 add(19)(p13) Liposarcoma, pleomorphic Soft tissue  
19p13 add(19)(p13) Malignant melanoma Eye  
19p13 add(19)(p13) Malignant peripheral nerve sheath tumor/Triton Soft tissue  
19p13 add(19)(p13) Mantle cell lymphoma    
19p13 add(19)(p13) Mature B-cell neoplasm, NOS    
19p13 add(19)(p13) Mature T- and NK-cell neoplasm, NOS    
19p13 add(19)(p13) Meningioma Brain  
19p13 add(19)(p13) Mesothelioma Pleura  
19p13 add(19)(p13) Multiple myeloma   31   
19p13 add(19)(p13) Mycosis fungoides/Sezary syndrome    
19p13 add(19)(p13) Myelodysplastic syndrome, NOS    
19p13 add(19)(p13) Myxofibrosarcoma Soft tissue  
19p13 add(19)(p13) Neuroblastoma Soft tissue  
19p13 add(19)(p13) Neuroblastoma Adrenal  
19p13 add(19)(p13) Osteoblastoma Skeleton  
19p13 add(19)(p13) Osteosarcoma, NOS Skeleton  
19p13 add(19)(p13) Refractory anemia    
19p13 add(19)(p13) Refractory anemia with excess blasts-2    
19p13 add(19)(p13) Refractory anemia with excess of blasts (FAB)    
19p13 add(19)(p13) Refractory anemia with ringed sideroblasts    
19p13 add(19)(p13) Squamous cell carcinoma Vagina  
19p13 add(19)(p13) Squamous cell carcinoma Oro- and hypopharynx  
19p13 add(19)(p13) Squamous cell carcinoma Oral cavity  
19p13 add(19)(p13) Squamous cell carcinoma Lung  
19p13 add(19)(p13) T-prolymphocytic leukemia    
19p13 add(19)(p13) Transitional cell carcinoma Bladder  
19p13 add(19)(p13) Undifferentiated pleomorphic sarcoma Soft tissue  
19p13 add(19)(p13) Wilms tumor Kidney  
19p13 add(19)(p13)oradd(19)(q13) Acute myeloid leukemia, NOS    
19p13 del(19)(p13) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
19p13 del(19)(p13) Acute monoblastic leukemia (FAB type M5)    
19p13 del(19)(p13) Adenocarcinoma Large intestine  
19p13 del(19)(p13) Adenocarcinoma Ovary  
19p13 del(19)(p13) Diffuse large B-cell lymphoma    
19p13 del(19)(p13) Mature B-cell neoplasm, NOS    
19p13 del(19)(p13p13) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
19p13 del(19)(p13p13) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
19p13 der(1)t(1;19)(p13;p13) Idiopathic myelofibrosis    
19p13 der(1)t(1;19)(p13;p13) Refractory anemia with ringed sideroblasts    
19p13 der(19)add(19)(p13)add(19)(q13) Adenocarcinoma Ovary  
19p13 der(19)add(19)(p13)add(19)(q13) Leiomyosarcoma Soft tissue  
19p13 der(19)add(19)(p13)add(19)(q13) Myxofibrosarcoma Soft tissue  
19p13 der(19)add(19)(p13)add(19)(q13) Osteosarcoma, NOS Skeleton  
19p13 der(19)del(19)(p13)del(19)(q11) Follicular lymphoma    
19p13 der(19)del(19)(p13)del(19)(q13) Mesothelioma Pleura  
19p13 der(19)t(10;19)(q11;p13) Acute megakaryoblastic leukemia (FAB type M7)    
19p13 der(19)t(11;19)(q13;p13) Adenocarcinoma Ovary  
19p13 der(19)t(11;19)(q13;p13) Diffuse large B-cell lymphoma    
19p13 der(19)t(11;19)(q13;p13) Multiple myeloma    
19p13 der(19)t(11;19)(q23;p13) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
19p13 der(19)t(12;19)(p13;p13) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
19p13 der(19)t(17;19)(q12;p13) Neuroblastoma Adrenal  
19p13 der(19)t(17;19)(q21;p13) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
19p13 der(19)t(17;19)(q21;p13) Adenocarcinoma Ovary  
19p13 der(19)t(17;19)(q22;p13) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
19p13 der(19)t(19;21)(p13;q11) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
19p13 der(19)t(1;19)(q10;p13) Meningioma Brain  
19p13 der(19)t(1;19)(q10;p13) Multiple myeloma    

Band Abnormality Morphology Topography Cases Genes
19p13 der(19)t(1;19)(q11;p13) Acute erythroleukemia (FAB type M6)    
19p13 der(19)t(1;19)(q11;p13) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
19p13 der(19)t(1;19)(q12;p13) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
19p13 der(19)t(1;19)(q12;p13) Multiple myeloma    
19p13 der(19)t(1;19)(q21;p13) Acute lymphoblastic leukemia/lymphoblastic lymphoma   13   
19p13 der(19)t(1;19)(q21;p13) Acute myeloid leukemia, NOS    
19p13 der(19)t(1;19)(q21;p13) Chondrosarcoma, NOS Skeleton  
19p13 der(19)t(1;19)(q23;p13) Acute lymphoblastic leukemia/lymphoblastic lymphoma   271   
19p13 der(19)t(1;19)(q23;p13) Bilineage or biphenotypic leukemia    
19p13 der(19)t(1;19)(q23;p13) Burkitt lymphoma/leukemia    
19p13 der(19)t(1;19)(q24;p13) Follicular lymphoma    
19p13 der(19)t(1;19)(q32;p13) Multiple myeloma    
19p13 der(19)t(3;19)(q11;p13) Adenocarcinoma Kidney  
19p13 der(19)t(5;19)(q14;p13) Ewing sarcoma Unknown site  
19p13 dic(19;22)(p13;q11) Meningioma Brain  
19p13 r(19)(p13q13) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
19p13 r(19)(p13q13) Undifferentiated pleomorphic sarcoma Soft tissue