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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

The Recurrent Chromosome Aberrations in Cancer Database Searcher
  • Brief instructions for searching the database:
    • You must choose one or both of the following two fields: Structural Aberrations and Numerical Aberrations.
    • If you choose Structural Aberrations, you must select at least one of the following fields: Breakpoint, Topography, Morphology, or Gene.
    • If you choose Numerical Aberrations, you must select at least one of the following fields: Chromosome, Topography, Morphology.
    • You may select only one item in each pulldown menu
    • Press Retrieve.
  • A successful search returns a table, with the following headings and entries:
    • Breakpoint, with each entry linked to the OMIM Gene Map (this column is returned only for structural aberrations)
    • Abnormality
    • Morphology, with each entry linked to a similar table that describes all abnormalities with this morphology.
    • Topography, with each entry linked to a similar table that describes all abnormalities at this topography
    • Number of cases, hyperlinked to the list of applicable cases
    • Genes

Aberration type:
Aberration type:




Expand Topography List:

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[Full Text]

Balanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
16q24 inv(16)(p11q24) Acute myeloid leukemia, NOS    
16q24 inv(16)(p13q24) Acute megakaryoblastic leukemia (FAB type M7)   CBFA2T3/GLIS2
16q24 t(11;16)(q23;q24) Acute monoblastic leukemia without differentiation (FAB type M5a)   KMT2A/USP10
16q24 t(13;16)(q14;q24) Chronic lymphocytic leukemia    
16q24 t(16;21)(q24;q22) Acute myeloblastic leukemia with maturation (FAB type M2)   15  RUNX1/CBFA2T3,RUNX1+
16q24 t(16;21)(q24;q22) Acute myeloblastic leukemia without maturation (FAB type M1)   RUNX1/CBFA2T3,RUNX1+
16q24 t(16;21)(q24;q22) Acute myeloid leukemia, NOS   RUNX1/CBFA2T3
16q24 t(16;21)(q24;q22) Acute myelomonocytic leukemia (FAB type M4)   RUNX1/CBFA2T3,RUNX1+
16q24 t(16;21)(q24;q22) Myelodysplastic syndrome, NOS   RUNX1/CBFA2T3,RUNX1+
16q24 t(16;22)(q24;q11) Chronic myeloid leukemia, aberrant translocation    
16q24 t(1;16)(p34;q24) Follicular lymphoma    
16q24 t(1;16)(q21;q24) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
16q24 t(9;22;16)(q34;q11;q24) Chronic myeloid leukemia, aberrant translocation   BCR/ABL1,BCR+

Unbalanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
16q24 add(16)(q24) Acute erythroleukemia (FAB type M6)    
16q24 add(16)(q24) Acute lymphoblastic leukemia/lymphoblastic lymphoma   20   
16q24 add(16)(q24) Acute megakaryoblastic leukemia (FAB type M7)    
16q24 add(16)(q24) Acute monoblastic leukemia (FAB type M5)    
16q24 add(16)(q24) Acute myeloblastic leukemia without maturation (FAB type M1)    
16q24 add(16)(q24) Acute myeloid leukemia, NOS   10   
16q24 add(16)(q24) Adenocarcinoma Liver  
16q24 add(16)(q24) Adenocarcinoma Ovary  
16q24 add(16)(q24) Adenocarcinoma Breast  
16q24 add(16)(q24) Adenocarcinoma Kidney  
16q24 add(16)(q24) Adenocarcinoma Large intestine  
16q24 add(16)(q24) Adenocarcinoma Lung  
16q24 add(16)(q24) Astrocytoma, grade III-IV/Glioblastoma Brain  
16q24 add(16)(q24) Burkitt lymphoma/leukemia    
16q24 add(16)(q24) Chondrosarcoma, NOS Skeleton  
16q24 add(16)(q24) Chronic lymphocytic leukemia    
16q24 add(16)(q24) Chronic myeloid leukemia, t(9;22)    
16q24 add(16)(q24) Diffuse large B-cell lymphoma    
16q24 add(16)(q24) Follicular lymphoma    
16q24 add(16)(q24) Leiomyosarcoma Soft tissue  
16q24 add(16)(q24) Malignant peripheral nerve sheath tumor/Triton Soft tissue  
16q24 add(16)(q24) Mantle cell lymphoma    
16q24 add(16)(q24) Mature B-cell neoplasm, NOS    
16q24 add(16)(q24) Mature T- and NK-cell neoplasm, NOS    
16q24 add(16)(q24) Multiple myeloma   21   
16q24 add(16)(q24) Mycosis fungoides/Sezary syndrome    
16q24 add(16)(q24) Myogenic sarcoma, NOS Soft tissue  
16q24 add(16)(q24) Peripheral T-cell lymphoma, unspecified    
16q24 add(16)(q24) Refractory anemia    
16q24 add(16)(q24) Refractory anemia with excess of blasts (FAB)    
16q24 add(16)(q24) Seminoma/Dysgerminoma Testis  
16q24 add(16)(q24) Squamous cell carcinoma Lung  
16q24 add(16)(q24) Squamous cell carcinoma Larynx  
16q24 add(16)(q24) Synovial sarcoma Soft tissue  
16q24 add(16)(q24) Teratoma (mature and immature) Testis  
16q24 add(16)(q24) Undifferentiated pleomorphic sarcoma Soft tissue  
16q24 del(16)(q22q24) Acute monoblastic leukemia (FAB type M5)    
16q24 del(16)(q22q24) Acute myeloid leukemia, NOS    
16q24 del(16)(q24) Liposarcoma, dedifferentiated Intraabdominal  
16q24 del(16)(q24) Malignant melanoma Skin  
16q24 der(16)(q24) Diffuse large B-cell lymphoma    
16q24 der(16)add(16)(p13)add(16)(q24) Anaplastic large cell lymphoma, systemic type    
16q24 der(16)t(11;16)(q13;q24) Acute myeloblastic leukemia without maturation (FAB type M1)    
16q24 der(16)t(11;16)(q13;q24) Mantle cell lymphoma    
16q24 der(16)t(1;16)(q12;q24) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
16q24 der(16)t(1;16)(q12;q24) Multiple myeloma    
16q24 der(16)t(1;16)(q21;q24) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
16q24 der(16)t(1;16)(q21;q24) Follicular lymphoma    
16q24 der(16)t(1;16)(q25;q24) Multiple myeloma    
16q24 der(16)t(7;16)(q11;q24) Adult T-cell lymphoma/leukemia (HTLV-1+)    
16q24 r(16)(p13q24) Acute lymphoblastic leukemia/lymphoblastic lymphoma