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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

The Recurrent Chromosome Aberrations in Cancer Database Searcher
  • Brief instructions for searching the database:
    • You must choose one or both of the following two fields: Structural Aberrations and Numerical Aberrations.
    • If you choose Structural Aberrations, you must select at least one of the following fields: Breakpoint, Topography, Morphology, or Gene.
    • If you choose Numerical Aberrations, you must select at least one of the following fields: Chromosome, Topography, Morphology.
    • You may select only one item in each pulldown menu
    • Press Retrieve.
  • A successful search returns a table, with the following headings and entries:
    • Breakpoint, with each entry linked to the OMIM Gene Map (this column is returned only for structural aberrations)
    • Abnormality
    • Morphology, with each entry linked to a similar table that describes all abnormalities with this morphology.
    • Topography, with each entry linked to a similar table that describes all abnormalities at this topography
    • Number of cases, hyperlinked to the list of applicable cases
    • Genes

Aberration type:
Aberration type:




Expand Topography List:

Expand Morphology List:

Expand Gene List:




[Full Text]

Balanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
16q23 t(14;16)(q32;q23) Multiple myeloma   IGH/MAF,IGH+
16q23 t(14;16)(q32;q23) Plasma cell leukemia    

Unbalanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
16q23 add(16)(q23) Adenocarcinoma Breast  
16q23 add(16)(q23) Diffuse large B-cell lymphoma    
16q23 add(16)(q23) Ependymoma Brain  
16q23 add(16)(q23) Multiple myeloma    
16q23 add(16)(q23) Peripheral T-cell lymphoma, unspecified    
16q23 del(16)(q23) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
16q23 del(16)(q23) Acute myeloid leukemia, NOS    
16q23 del(16)(q23) Adenocarcinoma Breast  
16q23 del(16)(q23) Mesothelioma Pleura  
16q23 del(16)(q23) Multiple myeloma    
16q23 der(16)t(1;16)(q21;q23) Wilms tumor Kidney  
16q23 der(16)t(1;16)(q25;q23) Acute myeloid leukemia, NOS    
16q23 der(16)t(1;16)(q31;q23) Multiple myeloma