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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

The Recurrent Chromosome Aberrations in Cancer Database Searcher
  • Brief instructions for searching the database:
    • You must choose one or both of the following two fields: Structural Aberrations and Numerical Aberrations.
    • If you choose Structural Aberrations, you must select at least one of the following fields: Breakpoint, Topography, Morphology, or Gene.
    • If you choose Numerical Aberrations, you must select at least one of the following fields: Chromosome, Topography, Morphology.
    • You may select only one item in each pulldown menu
    • Press Retrieve.
  • A successful search returns a table, with the following headings and entries:
    • Breakpoint, with each entry linked to the OMIM Gene Map (this column is returned only for structural aberrations)
    • Abnormality
    • Morphology, with each entry linked to a similar table that describes all abnormalities with this morphology.
    • Topography, with each entry linked to a similar table that describes all abnormalities at this topography
    • Number of cases, hyperlinked to the list of applicable cases
    • Genes

Aberration type:
Aberration type:




Expand Topography List:

Expand Morphology List:

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[Full Text]

Balanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
16q12 t(16;21)(q12;q22) Multiple myeloma    
16q12 t(1;16)(q21;q12) Multiple myeloma    

Unbalanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
16q12 add(16)(q12) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
16q12 add(16)(q12) Acute myeloblastic leukemia with maturation (FAB type M2)    
16q12 add(16)(q12) Acute myeloid leukemia, NOS    
16q12 add(16)(q12) Adenocarcinoma Kidney  
16q12 add(16)(q12) Ewing sarcoma Skeleton  
16q12 add(16)(q12) Multiple myeloma    
16q12 del(16)(q12) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
16q12 del(16)(q12) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
16q12 del(16)(q12) Acute myeloid leukemia, NOS    
16q12 del(16)(q12) Multiple myeloma    
16q12 del(16)(q12) Myelodysplastic syndrome, NOS    
16q12 del(16)(q12q22) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
16q12 der(16)del(16)(p11)del(16)(q12) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
16q12 der(16)t(16;17)(q12;q11) Acute myeloblastic leukemia without maturation (FAB type M1)    
16q12 der(16)t(1;16)(q12;q12) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
16q12 der(16)t(1;16)(q12;q12) Ewing sarcoma Skeleton  
16q12 der(16)t(1;16)(q12;q12) Multiple myeloma    
16q12 der(16)t(1;16)(q21;q12) Multiple myeloma    
16q12 der(16)t(1;16)(q21;q12) Wilms tumor Kidney