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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

The Recurrent Chromosome Aberrations in Cancer Database Searcher
  • Brief instructions for searching the database:
    • You must choose one or both of the following two fields: Structural Aberrations and Numerical Aberrations.
    • If you choose Structural Aberrations, you must select at least one of the following fields: Breakpoint, Topography, Morphology, or Gene.
    • If you choose Numerical Aberrations, you must select at least one of the following fields: Chromosome, Topography, Morphology.
    • You may select only one item in each pulldown menu
    • Press Retrieve.
  • A successful search returns a table, with the following headings and entries:
    • Breakpoint, with each entry linked to the OMIM Gene Map (this column is returned only for structural aberrations)
    • Abnormality
    • Morphology, with each entry linked to a similar table that describes all abnormalities with this morphology.
    • Topography, with each entry linked to a similar table that describes all abnormalities at this topography
    • Number of cases, hyperlinked to the list of applicable cases
    • Genes

Aberration type:
Aberration type:




Expand Topography List:

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[Full Text]

Balanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
16p11 inv(16)(p11q24) Acute myeloid leukemia, NOS    
16p11 t(11;16)(q13;p11) Acute myeloblastic leukemia with maturation (FAB type M2)    
16p11 t(12;16)(q13;p11) Liposarcoma, NOS Soft tissue  
16p11 t(12;16)(q13;p11) Liposarcoma, myxoid/round cell Intraabdominal  
16p11 t(12;16)(q13;p11) Liposarcoma, myxoid/round cell Soft tissue 90  DDIT3+,FUS/DDIT3
16p11 t(12;16)(q24;p11) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
16p11 t(15;16)(p11;p11) Multiple myeloma    
16p11 t(16;21)(p11;q22) Acute lymphoblastic leukemia/lymphoblastic lymphoma   ERG/FUS,FUS/ERG
16p11 t(16;21)(p11;q22) Acute megakaryoblastic leukemia (FAB type M7)   FUS/ERG
16p11 t(16;21)(p11;q22) Acute monoblastic leukemia with differentiation (FAB type M5b)   FUS/ERG
16p11 t(16;21)(p11;q22) Acute monoblastic leukemia without differentiation (FAB type M5a)   FUS/ERG
16p11 t(16;21)(p11;q22) Acute myeloblastic leukemia with maturation (FAB type M2)   13  ERG+,FUS/ERG
16p11 t(16;21)(p11;q22) Acute myeloblastic leukemia without maturation (FAB type M1)   18  ERG+,FUS/ERG
16p11 t(16;21)(p11;q22) Acute myeloid leukemia, NOS   ERG+,FUS/ERG
16p11 t(16;21)(p11;q22) Acute myelomonocytic leukemia (FAB type M4)   FUS/ERG
16p11 t(16;21)(p11;q22) Ewing sarcoma Skeleton FUS/ERG
16p11 t(1;16)(p36;p11) Benign fibrous histiocytoma Soft tissue  
16p11 t(2;16)(p11;p11) Acute lymphoblastic leukemia/lymphoblastic lymphoma   ZNF720/IGK
16p11 t(7;16)(q33;p11) Low-grade fibromyxoid sarcoma Soft tissue  
16p11 t(7;16)(q34;p11) Low-grade fibromyxoid sarcoma Soft tissue FUS/CREB3L2

Unbalanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
16p11 add(16)(p11) Acute erythroleukemia (FAB type M6)    
16p11 add(16)(p11) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
16p11 add(16)(p11) Acute myeloid leukemia, NOS    
16p11 add(16)(p11) Adenocarcinoma Breast  
16p11 add(16)(p11) Adenocarcinoma Kidney  
16p11 add(16)(p11) Adenocarcinoma Large intestine  
16p11 add(16)(p11) Adenocarcinoma Ovary  
16p11 add(16)(p11) Diffuse large B-cell lymphoma    
16p11 add(16)(p11) Mature B-cell neoplasm, NOS    
16p11 add(16)(p11) Multiple myeloma    
16p11 add(16)(p11) Osteosarcoma, NOS Skeleton  
16p11 add(16)(p11) Pleomorphic rhabdomyosarcoma Soft tissue  
16p11 add(16)(p11) Refractory anemia with excess of blasts (FAB)    
16p11 add(16)(p11) Undifferentiated pleomorphic sarcoma Soft tissue  
16p11 del(16)(p11) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
16p11 del(16)(p11) Adenocarcinoma Breast  
16p11 del(16)(p11) Adenocarcinoma Ovary  
16p11 del(16)(p11) Follicular lymphoma    
16p11 del(16)(p11) Malignant peripheral nerve sheath tumor/Triton Soft tissue  
16p11 del(16)(p11) Multiple myeloma    
16p11 der(1)t(1;16)(p11;p11) Liposarcoma, myxoid/round cell Soft tissue  
16p11 der(1)t(1;16)(p11;p11) Multiple myeloma    
16p11 der(12)t(12;16)(q13;p11) Liposarcoma, myxoid/round cell Soft tissue  
16p11 der(16)del(16)(p11)del(16)(q12) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
16p11 der(16)t(16;17)(p11;q11) Chronic lymphocytic leukemia    
16p11 der(21)t(16;21)(p11;q22) Acute myeloblastic leukemia without maturation (FAB type M1)    
16p11 dic(7;16)(q11;p11) Refractory anemia with excess of blasts (FAB)    
16p11 dup(16)(p11p13) Acute lymphoblastic leukemia/lymphoblastic lymphoma