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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

The Recurrent Chromosome Aberrations in Cancer Database Searcher
  • Brief instructions for searching the database:
    • You must choose one or both of the following two fields: Structural Aberrations and Numerical Aberrations.
    • If you choose Structural Aberrations, you must select at least one of the following fields: Breakpoint, Topography, Morphology, or Gene.
    • If you choose Numerical Aberrations, you must select at least one of the following fields: Chromosome, Topography, Morphology.
    • You may select only one item in each pulldown menu
    • Press Retrieve.
  • A successful search returns a table, with the following headings and entries:
    • Breakpoint, with each entry linked to the OMIM Gene Map (this column is returned only for structural aberrations)
    • Abnormality
    • Morphology, with each entry linked to a similar table that describes all abnormalities with this morphology.
    • Topography, with each entry linked to a similar table that describes all abnormalities at this topography
    • Number of cases, hyperlinked to the list of applicable cases
    • Genes

Aberration type:
Aberration type:




Expand Topography List:

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[Full Text]

Balanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
15q22 ins(15;17)(q22;q21q21) Acute promyelocytic leukemia (FAB type M3)   PML/CDC6/RARA,PML/RARA,PML/ADAMTS17/RARA
15q22 ins(17;15)(q12;q22q22) Acute promyelocytic leukemia (FAB type M3)    
15q22 ins(17;15)(q12;q22q22) Acute promyelocytic leukemia (FAB type M3)    
15q22 t(11;15;17)(q13;q22;q12) Acute promyelocytic leukemia (FAB type M3)    
15q22 t(15;17)(q22;q11) Acute myeloid leukemia, NOS   10   
15q22 t(15;17)(q22;q11) Acute promyelocytic leukemia (FAB type M3)   109   
15q22 t(15;17)(q22;q12) Acute myeloblastic leukemia without maturation (FAB type M1)    
15q22 t(15;17)(q22;q12) Acute myeloid leukemia, NOS   12   
15q22 t(15;17)(q22;q12) Acute promyelocytic leukemia (FAB type M3)   266   
15q22 t(15;17)(q22;q12) Chronic myeloid leukemia, t(9;22)    
15q22 t(15;17)(q22;q21) Acute myeloblastic leukemia with maturation (FAB type M2)   PML/RARA
15q22 t(15;17)(q22;q21) Acute myeloblastic leukemia without maturation (FAB type M1)   PML/RARA
15q22 t(15;17)(q22;q21) Acute myeloid leukemia, NOS   PML/RARA
15q22 t(15;17)(q22;q21) Acute promyelocytic leukemia (FAB type M3)   624  PML/RARA,RARA+
15q22 t(15;17)(q22;q21) Bilineage or biphenotypic leukemia   PML/RARA
15q22 t(15;17)(q22;q21) Chronic myeloid leukemia, t(9;22)   PML/RARA
15q22 t(15;17)(q22;q22) Acute promyelocytic leukemia (FAB type M3)    
15q22 t(15;21)(q22;q22) Chronic myeloid leukemia, t(9;22)    
15q22 t(9;15)(q34;q22) Multiple myeloma    
15q22 t(9;22;15)(q34;q11;q22) Chronic myeloid leukemia, aberrant translocation   BCR/ABL1,BCR+

Unbalanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
15q22 add(15)(q22) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
15q22 add(15)(q22) Acute myeloid leukemia, NOS    
15q22 add(15)(q22) Acute promyelocytic leukemia (FAB type M3)    
15q22 add(15)(q22) Adenocarcinoma Large intestine  
15q22 add(15)(q22) Astrocytoma, grade III-IV/Glioblastoma Brain  
15q22 add(15)(q22) Bilineage or biphenotypic leukemia    
15q22 add(15)(q22) Diffuse large B-cell lymphoma    
15q22 add(15)(q22) Follicular lymphoma    
15q22 add(15)(q22) Leiomyosarcoma Soft tissue  
15q22 add(15)(q22) Malignant peripheral nerve sheath tumor/Triton Soft tissue  
15q22 add(15)(q22) Mantle cell lymphoma    
15q22 add(15)(q22) Mature B-cell neoplasm, NOS    
15q22 add(15)(q22) Multiple myeloma    
15q22 add(15)(q22) Myxofibrosarcoma Soft tissue  
15q22 add(15)(q22) Seminoma/Dysgerminoma Testis  
15q22 add(15)(q22) Squamous cell carcinoma Oral cavity  
15q22 add(15)(q22) Synovial sarcoma Soft tissue  
15q22 del(15)(q15q22) Acute myeloid leukemia, NOS    
15q22 del(15)(q15q22) Acute myelomonocytic leukemia (FAB type M4)    
15q22 del(15)(q15q22) Chronic myeloid leukemia, t(9;22)    
15q22 del(15)(q15q22) Diffuse large B-cell lymphoma    
15q22 del(15)(q22) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
15q22 del(15)(q22) Adenocarcinoma Kidney  
15q22 del(15)(q22) Adenoma Salivary gland  
15q22 del(15)(q22) Chondroid hamartoma Lung  
15q22 del(15)(q22) Chronic myeloid leukemia, t(9;22)    
15q22 del(15)(q22) Diffuse large B-cell lymphoma    
15q22 del(15)(q22) Follicular lymphoma    
15q22 del(15)(q22) Neuroblastoma Adrenal  
15q22 del(15)(q22) Splenic marginal zone B-cell lymphoma    
15q22 del(15)(q22) Synovial sarcoma Soft tissue  
15q22 del(15)(q22q24) Diffuse large B-cell lymphoma    
15q22 del(15)(q22q26) Acute promyelocytic leukemia (FAB type M3)    
15q22 del(15)(q22q26) Mycosis fungoides/Sezary syndrome    
15q22 der(15)t(15;17)(q22;q11) Acute promyelocytic leukemia (FAB type M3)    
15q22 der(15)t(15;17)(q22;q12) Acute promyelocytic leukemia (FAB type M3)   10   
15q22 der(15)t(15;17)(q22;q21) Acute promyelocytic leukemia (FAB type M3)   23   
15q22 der(15)t(9;15)(q31;q22) Mycosis fungoides/Sezary syndrome    
15q22 der(19)t(15;19)(q22;q11) Mantle cell lymphoma