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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

The Recurrent Chromosome Aberrations in Cancer Database Searcher
  • Brief instructions for searching the database:
    • You must choose one or both of the following two fields: Structural Aberrations and Numerical Aberrations.
    • If you choose Structural Aberrations, you must select at least one of the following fields: Breakpoint, Topography, Morphology, or Gene.
    • If you choose Numerical Aberrations, you must select at least one of the following fields: Chromosome, Topography, Morphology.
    • You may select only one item in each pulldown menu
    • Press Retrieve.
  • A successful search returns a table, with the following headings and entries:
    • Breakpoint, with each entry linked to the OMIM Gene Map (this column is returned only for structural aberrations)
    • Abnormality
    • Morphology, with each entry linked to a similar table that describes all abnormalities with this morphology.
    • Topography, with each entry linked to a similar table that describes all abnormalities at this topography
    • Number of cases, hyperlinked to the list of applicable cases
    • Genes

Aberration type:
Aberration type:




Expand Topography List:

Expand Morphology List:

Expand Gene List:




[Full Text]

Balanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
15q21 t(15;17)(q21;q12) Acute promyelocytic leukemia (FAB type M3)    
15q21 t(15;21)(q21;q22) Acute myeloid leukemia, NOS   RUNX1/TCF12
15q21 t(6;15)(p21;q21) Oncocytoma Kidney  
15q21 t(9;22;15)(q34;q11;q21) Chronic myeloid leukemia, aberrant translocation   BCR/ABL1

Unbalanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
15q21 add(15)(q21) Acute myeloblastic leukemia with maturation (FAB type M2)    
15q21 add(15)(q21) Follicular lymphoma    
15q21 add(15)(q21) Multiple myeloma    
15q21 del(15)(q11q21) Acute myeloblastic leukemia without maturation (FAB type M1)    
15q21 del(15)(q11q21) Acute myelomonocytic leukemia (FAB type M4)    
15q21 del(15)(q21) Acute myeloid leukemia, NOS    
15q21 del(15)(q21) Burkitt lymphoma/leukemia    
15q21 del(15)(q21) Chronic myeloid leukemia, t(9;22)    
15q21 del(15)(q21) Diffuse large B-cell lymphoma