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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. ALOX5, Arachidonate 5-lipoxygenase
Sequence ID:NM_000698
NM_001256153
NM_001256154
RefSeqGene ID:NG_011437
Entrez Gene ID:240
Ensembl ID:ENSG00000012779

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
ASTHMAADRB2
CCL11
HLA-G
HNMT
IL12B
IL13
MUC7
PHF11
PLA2G7
SCGB1A1
SCGB3A2
TNF

Cytogenetic Location (from UniGene)

Cytogenetic Location:10q11.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:10: 45869660 - 45924120


Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
9052503Full LengthBC143985arachidonate 5-lipoxygenase
40146363Full LengthBC130332arachidonate 5-lipoxygenase
40146699Full LengthBC132677arachidonate 5-lipoxygenase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000689  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000698 NP_000689 P09917 EC 1.13.11.34 Lipoxygenase
PLAT
NM_001256153 NP_001243082      
NM_001256154 NP_001243083      

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
J03600 AAA36183 P09917 EC 1.13.11.34
J03571 AAA65450 P09917 EC 1.13.11.34
BC130332 AAI30333 P09917 EC 1.13.11.34
BC132677 AAI32678 P09917 EC 1.13.11.34
BC143985 AAI43986 B7ZLS0  
HM592258 ADR30798 E5FPY5  
HM592259 ADR30799 B7ZLS0  
HM592260 ADR30800 E5FPY7  
HM592261 ADR30801 E5FPY8  
HQ258335 ADR83089    
JQ728550 AFH78150 I0CLG0  
AB208946 BAD92183 Q59H13  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens ALOX5 NP_000689 M.musculus Alox5 11689 Gene Info NP_033792 93
R.norvegicus Alox5 25290   NP_036954 93
A.thaliana LOX1 841944   NP_175900 33
A.thaliana LOX5 821808   NP_188879 33

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta