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Gene Info

Gene Information For:Hs. NFKBIA, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
Sequence ID:NM_020529
RefSeqGene ID:NG_007571
Entrez Gene ID:4792
Ensembl ID:ENSG00000100906

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
ECTODERMAL DYSPLASIA, ANHIDROTIC, WITH T-CELL IMMUNODEFICIENCY 

Cytogenetic Location (from UniGene)

Cytogenetic Location:14q13Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:14: 35870963 - 35873955

NM_020529 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
145633587071635871265
5648333587159935871868
8349223587197635872064
92311333587235535872565
113412423587289535873003
124315793587362335873959

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2957970Full LengthBC004983nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
3161686Full LengthBC002601nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_065390  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_020529 NP_065390 P25963 Ank

Related Sequences

 
mRNAGenPeptSwissProt
M69043 AAA16489 P25963
BC002601 AAH02601 P25963
BC004983 AAH04983 P25963
AY033600 AAK51149 P25963
BT007091 AAP35754 P25963
AK313421 BAG36213 P25963

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens NFKBIA NP_065390 M.musculus Nfkbia 18035 Gene Info NP_035037 92
R.norvegicus Nfkbia 25493   NP_001099190 92
D.melanogaster cact 34969   NP_476942 41
A.gambiae CACT 1278017   XP_317542 35

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

NCI-Nature Pathway Interaction Database

BioCarta Pathways
Pathway information courtesy of BioCarta