Skip Navigation
National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. PGK1, Phosphoglycerate kinase 1
Sequence ID:NM_000291
RefSeqGene ID:NG_008862
Entrez Gene ID:5230
Ensembl ID:ENSG00000102144

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
PHOSPHOGLYCERATE KINASE 1 DEFICIENCY 

Cytogenetic Location (from UniGene)

Cytogenetic Location:Xq13.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:X: 77359768 - 77382324

 Exon Info From UCSC:
NM_000291

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3917985Full LengthBC023234phosphoglycerate kinase 1
6526214Full LengthBC103752phosphoglycerate kinase 1
8143840Full LengthBC104837phosphoglycerate kinase 1
8322620Full LengthBC113568phosphoglycerate kinase 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000282  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000291 NP_000282 P00558 EC 2.7.2.3 PGK

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
L00160 AAA60078 P00558 EC 2.7.2.3
BC023234 AAH23234 P00558 EC 2.7.2.3
BC103752 AAI03753 P00558 EC 2.7.2.3
BC104837 AAI04838 P00558 EC 2.7.2.3
BC113568 AAI13569 P00558 EC 2.7.2.3
AY423725 AAS00488 P00558 EC 2.7.2.3
HQ258236 ADR82990    
D28371 BAA05737    
AB062432 BAB93495 P00558 EC 2.7.2.3
AK291081 BAF83770 P00558 EC 2.7.2.3
AK312280 BAG35209 P00558 EC 2.7.2.3
AK295014 BAG58074 B4DHB3  
AK295182 BAG58187 B4DHM5  
AK298855 BAG60978 B4DHM5  
AK301632 BAG63115 B4DWQ3  
AK303848 BAG64791 B4E1H9  
AK301740 BAH13545 B7Z7A9  
V00572 CAA23835 P00558 EC 2.7.2.3
CR456716 CAG32997 P00558 EC 2.7.2.3

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PGK1 NP_000282 M.musculus Pgk1 18655 Gene Info NP_032854 98
R.norvegicus Pgk1 24644   NP_445743 97
A.gambiae AgaP_AGAP008802 1275659   XP_314928 73
C.elegans pgk-1 171965   NP_491245 73
D.melanogaster Pgk 33461   NP_476676 71
N.crassa NCU07914 3878602   XP_962430 69
S.pombe pgk1 2539764   NP_596730 67
S.cerevisiae PGK1 850370   NP_009938 66
P.falciparum PGK 813501   XP_001352096 61

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

NCI-Nature Pathway Interaction Database