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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. DLEC1, deleted in lung and esophageal cancer 1
Sequence ID:NM_007335
NM_007337
NM_007336
NM_007338
RefSeqGene ID:NG_023237
Entrez Gene ID:9940
Ensembl ID:ENSG00000008226

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
ADENOCARCINOMA OF LUNG, RESPONSE TO TYROSINE KINASE INHIBITOR INBRAF
CASP8
CYP2A6
EGFR
ERBB2
ERCC6
FASLG
IRF1
KRAS
MAP3K8
MAP3K8
PARK2
PIK3CA
PIK3CA
PPP2R1B
RASSF1
SLC22A18
ESOPHAGEAL CANCER, SOMATICDEC1
LZTS1
RNF6
TGFBR2
TGFBR2
WWOX

Cytogenetic Location (from UniGene)

Cytogenetic Location:3p21.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:3: 38080695 - 38164229

 Exon Info From UCSC:
NM_007335
NM_007337

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
9054453Full LengthBC171799deleted in lung and esophageal cancer 1
100069102Full LengthBC172408deleted in lung and esophageal cancer 1
40113683IncompleteBC129825deleted in lung and esophageal cancer 1

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_007335 NP_031361 Q9Y238  
NM_007337 NP_031363    

Related Sequences

 
mRNAGenPeptSwissProt
BC129824 AAI29825 A1L305
BC129825 AAI29826 A2VDF1
BC171799 AAI71799 B7ZW06
BC172408 AAI72408  
AY789462 AAX18633 Q32W78
AY789463 AAX18634 Q32W77
AY789464 AAX18635 Q32W76
AB020522 BAA77247 Q9Y238
AB425198 BAG11659 B1B5Y4
AK302803 BAG64005 B4DZ93
AL137282 CAB70676 Q9Y238
AL137706 CAB70884 Q9Y238

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens DLEC1 NP_031361 M.musculus Dlec1 320256 Gene Info NP_796091 72

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)