Skip Navigation
National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. ASCL1, achaete-scute complex homolog 1 (Drosophila)
Sequence ID:NM_004316
RefSeqGene ID:NG_008950
Entrez Gene ID:429
Ensembl ID:ENSG00000139352

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssemblies

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
CENTRAL HYPOVENTILATION SYNDROMEBDNF
EDN3
GDNF
PHOX2B
RET

Cytogenetic Location (from UniGene)

Cytogenetic Location:12q23.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:12: 103351451 - 103353461

NM_004316 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
11329103351451103352779
13302477103353139103354286

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2819879Full LengthBC004425achaete-scute complex homolog 1 (Drosophila)
2821173Full LengthBC002341achaete-scute complex homolog 1 (Drosophila)
2821173Full LengthBC003134achaete-scute complex homolog 1 (Drosophila)
3534115Full LengthBC031299achaete-scute complex homolog 1 (Drosophila)
2819879IncompleteBC001638achaete-scute complex homolog 1 (Drosophila)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_004307  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_004316 NP_004307 P50553 HLH

Related Sequences

 
mRNAGenPeptSwissProt
L08424 AAA58376 P50553
BC002341 AAH02341 P50553
BC003134 AAH03134 P50553
BC004425 AAH04425 P50553
BC031299 AAH31299 P50553
DQ894571 ABM85497  
EU176303 ABW03754  
AK290539 BAF83228 P50553

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens ASCL1 NP_004307 R.norvegicus Ascl1 64186   NP_071779 97
M.musculus Ascl1 17172 Gene Info NP_032579 96

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

NCI-Nature Pathway Interaction Database