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Gene Info

Gene Information For:Hs. IL12B, Interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
Sequence ID:NM_002187
RefSeqGene ID:NG_009618
Entrez Gene ID:3593
Ensembl ID:ENSG00000113302

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
ASTHMAADRB2
ALOX5
CCL11
HLA-G
HNMT
IL13
MUC7
PHF11
PLA2G7
SCGB1A1
SCGB3A2
TNF
BCG INFECTION, GENERALIZED FAMILIALIFNGR1
IFNGR2
IL12RB1
STAT1
STAT1
PSORIASIS SUSCEPTIBILITY 1HLA-C
HLA-C
HLA-C
IL23R

Cytogenetic Location (from UniGene)

Cytogenetic Location:5q31.1-q33.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:5: 158743095 - 158753792

NM_002187 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
11318158741790158743107
13191450158743692158743823
14511608158745743158745900
16091823158747313158747527
18241941158749401158749518
19422217158750061158750336
22182305158753702158753789
23062347158757439158757480

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
6971868Full LengthBC067498interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
6971869Full LengthBC067499interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
6971872Full LengthBC067500interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
6971873Full LengthBC067501interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
6971874Full LengthBC067502interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
30915173Full LengthBC074723interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_002187 NP_002178 P29460 fn3

Related Sequences

 
mRNAGenPeptSwissProt
M65272 AAA35695 P29460
M65290 AAA59938 P29460
AF180563 AAD56386 P29460
BC067498 AAH67498 P29460
BC067499 AAH67499 P29460
BC067500 AAH67500 P29460
BC067501 AAH67501 P29460
BC067502 AAH67502 P29460
BC074723 AAH74723 P29460
AY046592 AAL05890 Q8N0X8
AY046593 AAL05891 Q8N0X8
EF173865 ABM53138 A1Z2L5
HQ447568 ADQ32054  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens IL12B NP_002178 M.musculus Il12b 16160 Gene Info NP_032378 70
R.norvegicus Il12b 64546   NP_072133 69

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

NCI-Nature Pathway Interaction Database

BioCarta Pathways
Pathway information courtesy of BioCarta