Skip Navigation
National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools

Gene Info

Gene Information For:Hs. HLA-C, Major histocompatibility complex, class I, C
Sequence ID:NR_027822
RefSeqGene ID:NG_029422
Entrez Gene ID:3107
Ensembl ID:ENSG00000204525

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
AIDS, RAPID PROGRESSION TOCCL11
CCL2
CCL3
CCL3L1
CD209
CX3CR1
CXCL12
CXCR1
IFNG
IL10
IL4R
IL4R
KIR3DL1
PSORIASIS SUSCEPTIBILITY 1IL12B
IL23R

Cytogenetic Location (from UniGene)

Cytogenetic Location:6p21.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:6: 30227373 - 30234728


Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3345005Full LengthBC002463major histocompatibility complex, class I, C
4249847Full LengthBC008457major histocompatibility complex, class I, C
4780246Full LengthBC033293major histocompatibility complex, class I, C
3459298IncompleteBC010542major histocompatibility complex, class I, C
3678099IncompleteBC004489major histocompatibility complex, class I, C
4299697IncompleteBC007814major histocompatibility complex, class I, C

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001243042 NP_001229971    
NM_002117 NP_002108 Q6R739
Q95HC2
P10321
MHC_I
MHC_I_C
C1-set

Related Sequences

 
mRNAGenPeptSwissProt
M24031 AAA00027 Q8SNA8
U07230 AAA17037 Q29645
M28160 AAA36235 Q29963
U09853 AAA50217 P10321
M11886 AAA52665 P10321
M26712 AAA52666 O19677
M28207 AAA53259 P10321
M28206 AAA57258 Q29963
M24096 AAA59654 Q29958
M24097 AAA59656 Q29960
M24097 AAA59657 Q29960
M84171 AAA59685 Q7YNW6
P30499
M84172 AAA59686 Q7YQB3
P04222
M84173 AAA59687 P30505
M84174 AAA59688 P30505
Q546I7
M12679 AAA59699 Q14838
M26429 AAA59701 P30499
M26430 AAA59703 P30501
M26431 AAA59704 Q29988
M84386 AAA59705 Q5D1W8
P30504
M21963 AAA59847 P30508
M99389 AAA88088 Q53YP1
P04222
M99390 AAA88089 P04222
U06695 AAA92995 P30508
Q96FQ5
U06696 AAA92996 P30508
Q96FQ5
U62824 AAB67322 Q95604
U41420 AAC32742 O78179
U41386 AAC32743 P30510
U91179 AAC51396  
U57028 AAD11469 Q9TNN7
Q5RIP0
S74115 AAD14147 Q29658
AF168611 AAD50823 Q9TNN7
L38251 AAF26750 Q9MY34
BC002463 AAH02463 O78179
BC007814 AAH07814 Q6R739
Q95HC2
P10321
BC008457 AAH08457 Q96QL3
BC010542 AAH10542 Q96FQ5
BC033293 AAH33293 O19617
BC139904 AAI39905 Q6ZSK9
BC141846 AAI41847 A5D8X1
AF405691 AAL03994 Q95HN1
L77114 AAL40067 Q9TPQ8
Q9GJG4
Q8WLR2
AF196489 AAM76870 Q95HN1
AY732487 AAV33126 Q5UGI4
DQ891896 ABM82822  
DQ895082 ABM86008  
D38526 BAA07531 Q6R739
Q95HC2
P10321
D49552 BAA08500 Q7YQB2
P10321
D49819 BAA08625 Q6R739
Q95HC2
P10321
D83029 BAA11747 P79497
D64145 BAA19531 P30499
D64146 BAA19532 P30508
D64147 BAA19533 O19657
D64148 BAA19534 Q9TNN7
D64150 BAA19535 O19653
D64151 BAA19536 O19655
D64152 BAA19537 P30508
D50853 BAA32610 P04222
D50852 BAA32611 Q7YNW6
D50854 BAA32612 Q53X46
D83030 BAA32613 O78164
D83741 BAA32615 P30508
AK127349 BAC86939 Q6ZSK9
AK301283 BAG62842 B4DVY0
AK304527 BAG65328 B4E316
AJ005199 CAA06438 Q9TNU1
AJ010748 CAA09340 Q9TNN7
Q5RIP0
AJ010749 CAA09341 P10321
X58536 CAA41427 Q5D1W8
P30504
X70856 CAA50209 P30508
Q546I6
X70857 CAA50210 Q29963
P30508
Q5QT33
X76189 CAA53783 Q29960
X82122 CAA57634 P30508
Q96FQ5
X83394 CAA58313 Q7YQB2
P10321
X97321 CAA65986 P10321
X98742 CAA67294 Q95604
X99704 CAA68035 P30508
Y10520 CAA71531 Q95604
Y11843 CAA72592 P30508
Z15144 CAA78850 P30505
Q53X46
Z33459 CAA83881 Q29866
Z46809 CAA86839 P30499
Z46810 CAA86840 P10321
Z83247 CAB05845 P30508
AJ440716 CAD29433 Q8SNB1
AJ537578 CAD61205 Q861B1
AM237285 CAJ86551 Q1XDY2

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens HLA-C NP_002108 M.musculus H2-D1 14964   NP_034510 69
M.musculus H2-K1 14972 Gene Info NP_001001892 67
R.norvegicus RT1-CE15 414789   NP_001008838 66
R.norvegicus RT1-A3 309627   NP_001008830 66
R.norvegicus RT1-A2 24974   NP_001008829 66
R.norvegicus RT1-CE12 309600   NP_001008835 65
R.norvegicus RT1-CE1 309603   NP_001008832 65
R.norvegicus RT1-CE7 368153   NP_001008845 65
R.norvegicus RT1-CE3 414793   NP_001008841 65
R.norvegicus RT1-CE2 414779   NP_001008840 65
R.norvegicus RT1-A1 24973   NP_001008827 65
R.norvegicus RT1-Cl 24977   NP_996730 64
R.norvegicus RT1-CE4 414783   NP_001008842 64
R.norvegicus RT1-CE13 414790   NP_001008836 64
R.norvegicus RT1-CE10 414792   NP_001008833 64
R.norvegicus RT1-CE5 309607   NP_001029158 63
R.norvegicus RT1-CE11 414791   NP_001008834 62
R.norvegicus RT1-CE16 414819   NP_001008839 62

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)