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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. ALK, anaplastic lymphoma receptor tyrosine kinase
Sequence ID:NM_004304
RefSeqGene ID:NG_009445
Entrez Gene ID:238
Ensembl ID:ENSG00000171094

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
NEUROBLASTOMAKIF1B
NME1
PHOX2B
NEUROBLASTOMA 

Cytogenetic Location (from UniGene)

Cytogenetic Location:2p23Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 29415642 - 30144014

 Exon Info From UCSC:
NM_004304

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
100063409Full LengthBC157090anaplastic lymphoma receptor tyrosine kinase
100061564BC156207anaplastic lymphoma receptor tyrosine kinase

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_004304 NP_004295 Q9UM73 EC 2.7.10.1  

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U62540 AAB71619 Q9UM73 EC 2.7.10.1
U66559 AAC51104 Q9UM73 EC 2.7.10.1
BC156207 AAI56208 Q9UM73 EC 2.7.10.1
BC157090 AAI57091    
EU788003 ACI47591 B6D4Y1  
EU788004 ACI47592 B6D4Y2  
EU788005 ACI47593 B6D4Y3  
EU788006 ACI47594 B6D4Y3  
EU788007 ACI47595 B6D4Y5  
EU788008 ACI47596 B6D4Y6  
EU788009 ACI47597 B6D4Y7  
EU788010 ACI47598 B6D4Y8  
GU128152 ACY79560 D1MAM0  
GU128153 ACY79561 D1MAM1  
GU128154 ACY79562 D1MAM2  
GU128155 ACY79563 D1MAM3  
GU128156 ACY79564 D1MAM4  
GU128157 ACY79565 D1MAM5  
FJ838786 ACZ57900 F0UY65  
FJ838787 ACZ57901 F0UY66  
AB209477 BAD92714 Q9UM73 EC 2.7.10.1
AK296218 BAG58942 B4DJT0  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens ALK NP_004295 R.norvegicus Alk 266802   NP_001162572 89
M.musculus Alk 11682 Gene Info NP_031465 88
A.gambiae AgaP_AGAP012070 1280600   XP_320455 40
D.melanogaster Alk 53425   NP_652600 38

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)