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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. ERCC6, excision repair cross-complementing rodent repair deficiency, complementation group 6
Sequence ID:NM_000124
RefSeqGene ID:NG_009442
Entrez Gene ID:2074
Ensembl ID:ENSG00000225830

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
ADENOCARCINOMA OF LUNG, RESPONSE TO TYROSINE KINASE INHIBITOR INBRAF
CASP8
CYP2A6
DLEC1
EGFR
ERBB2
FASLG
IRF1
KRAS
MAP3K8
MAP3K8
PARK2
PIK3CA
PIK3CA
PPP2R1B
RASSF1
SLC22A18
CEREBROOCULOFACIOSKELETALSYNDROME 1ERCC5
COCKAYNE SYNDROME, TYPE B 
DE SANCTIS-CACCHIONE SYNDROME 
MACULAR DEGENERATION, AGE-RELATED, 5 
UV-SENSITIVESYNDROME 1 

Cytogenetic Location (from UniGene)

Cytogenetic Location:10q11.23Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:10: 50723246 - 50732273

 Exon Info From UCSC:
NM_000124

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
40124639Full LengthBC127104excision repair cross-complementing rodent repair deficiency, complementation group 6

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000115  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000124 NP_000115 Q03468 SNF2_N
Helicase_C
NM_170753 NP_736609 Q8N328  

Related Sequences

 
mRNAGenPeptSwissProt
L04791 AAA52397 Q03468
BC028954 AAH28954 Q8N328
BC034479 AAH34479 Q8N328
BC063690 AAH63690 Q8N328
BC127104 AAI27105 A0JP10
AB209504 BAD92741 Q59FF6
AK291018 BAF83707 A8K4Q3
AK074682 BAG51986 Q8N328
AK303022 BAG64148 B4DZN6
AL133084 CAB61402 Q9UIW3
CR749388 CAH18238 Q68DI2

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens ERCC6 NP_000115 M.musculus Ercc6 319955 Gene Info NP_001074690 80
R.norvegicus Ercc6 306274   NP_001100766 80
S.cerevisiae RAD26 853492   NP_012569 54
A.thaliana CHR8 816391   NP_179466 53
S.pombe rhp26 2539473   NP_588091 53
N.crassa NCU07837 3879106   XP_962958 50

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)