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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. WT1, Wilms tumor 1
Sequence ID:NM_000378
NM_001198551
NM_001198552
NM_024424
NM_024426
NM_024425
RefSeqGene ID:NG_009272
Entrez Gene ID:7490
Ensembl ID:ENSG00000184937

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
DENYS-DRASH SYNDROME 
FRASIER SYNDROME 
MEACHAM SYNDROME 
MESOTHELIOMA, SOMATICBCL10
NEPHROTIC SYNDROME, TYPE 4 
WILMS TUMORBRCA2
GPC3

Cytogenetic Location (from UniGene)

Cytogenetic Location:11p13Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:11: 32409323 - 32452359

 Exon Info From UCSC:
NM_000378
NM_024424
NM_024426
NM_024425

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4827849Full LengthBC032861Wilms tumor 1
5169770IncompleteBC046461Wilms tumor 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_077744  NP_000369  NP_077742  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000378 NP_000369   zf-C2H2
WT1
NM_001198551 NP_001185480    
NM_001198552 NP_001185481    
NM_024424 NP_077742   zf-C2H2
WT1
NM_024426 NP_077744   zf-C2H2
WT1

Related Sequences

 
mRNAGenPeptSwissProt
M30393 AAA36810 P19544
S74529 AAB33427  
S75264 AAB33443 P19544
BC032861 AAH32861 P19544
BC046461 AAH46461 Q6PI38
JF432657 ADZ15874  
AK291736 BAF84425 P19544
AK093168 BAG52667 P19544
X51630 CAA35956 P19544

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens WT1 NP_077744 R.norvegicus Wt1 24883   NP_113722 98
M.musculus Wt1 22431 Gene Info NP_659032 94

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

NCI-Nature Pathway Interaction Database

BioCarta Pathways
Pathway information courtesy of BioCarta