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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. IL7R, Interleukin 7 receptor
Sequence ID:NM_002185
RefSeqGene ID:NG_009567
Entrez Gene ID:3575
Ensembl ID:ENSG00000168685

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
MULTIPLE SCLEROSISCD24
CIITA
HLA-DQB1
HLA-DQB1
HLA-DRB1
HLA-DRB1
HLA-DRB1
PDCD1
PTPRC
SEVERE COMBINED IMMUNODEFICIENCY, T CELL-NEGATIVE, B-CELL/NATURALKILLER-CELL POSITIVECD3D
CD3E
PTPRC

Cytogenetic Location (from UniGene)

Cytogenetic Location:5p13Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:5: 35879025 - 35879705

NM_002185 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
11713585699035857160
1723103586095335861091
3114683586740735867564
4696263587115735871314
6277953587358135873749
7968893587455035874643
8909653587561335875688
96618023587608435876920

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
6971840Full LengthBC067537interleukin 7 receptor
6971842Full LengthBC067538interleukin 7 receptor
6971843Full LengthBC069999interleukin 7 receptor
6971844Full LengthBC067539interleukin 7 receptor
6971846Full LengthBC067540interleukin 7 receptor
4771221IncompleteBC020717interleukin 7 receptor

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002176  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_002185 NP_002176   fn3

Related Sequences

 
mRNAGenPeptSwissProt
M29696 AAA59157 P16871
BC020717 AAH20717 P16871
BC067537 AAH67537 P16871
BC067538 AAH67538 P16871
BC067539 AAH67539 P16871
BC067540 AAH67540 P16871
BC069999 AAH69999 P16871
FJ529208 ACL80333 B8YG18
HQ447513 ADQ31999  
AK315251 BAG37673 P16871
AK301220 BAG62793 P16871

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens IL7R NP_002176 R.norvegicus Il7r 294797   NP_001099888 66
M.musculus Il7r 16197 Gene Info NP_032398 65

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta