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Gene Info

Gene Information For:Hs. PPP2R1B, protein phosphatase 2, regulatory subunit A, beta
Sequence ID:NM_001177562
NM_001177563
NM_002716
NM_181699
NM_181700
RefSeqGene ID:NG_012117
Entrez Gene ID:5519
Ensembl ID:ENSG00000137713

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
ADENOCARCINOMA OF LUNG, RESPONSE TO TYROSINE KINASE INHIBITOR INBRAF
CASP8
CYP2A6
DLEC1
EGFR
ERBB2
ERCC6
FASLG
IRF1
KRAS
MAP3K8
MAP3K8
PARK2
PIK3CA
PIK3CA
RASSF1
SLC22A18

Cytogenetic Location (from UniGene)

Cytogenetic Location:11q23.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:11: 111612232 - 111637113

 Exon Info From UCSC:
NM_001177562
NM_001177563
NM_002716
NM_181699
NM_181700

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4831056Full LengthBC027596protein phosphatase 2 (formerly 2A), regulatory subunit A, beta isoform

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002707  NP_859050  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001177562 NP_001171033    
NM_001177563 NP_001171034    
NM_002716 NP_002707 P30154 HEAT
NM_181699 NP_859050   HEAT
NM_181700 NP_859051    

Related Sequences

 
mRNAGenPeptSwissProt
M65254 AAA59983 P30154
AF087438 AAC69624 P30154
AF163473 AAG39644 P30154
BC027596 AAH27596 P30154
DQ894107 ABM85033  
DQ890606 ABM92223  
EU176538 ABW03339  
AK292275 BAF84964 A8K8B0
AK294716 BAG57867 B4DGQ6
AK296455 BAG59103 B4DK91
AK301705 BAG63177 P30154
AK293388 BAH11499 B7Z1G3

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PPP2R1B NP_859050 R.norvegicus Ppp2r1b 315648   NP_001020589 96
M.musculus Ppp2r1b 73699 Gene Info NP_001029257 94
A.thaliana RCN1 839135   NP_173920 58

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)