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Gene Info

Gene Information For:Hs. SERPINA1, Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
Sequence ID:NM_001127701
NM_001002236
NM_001127705
NM_001127703
NM_001127704
NM_001127702
NM_001127706
NM_001127707
NM_001127700
NM_000295
NM_001002235
RefSeqGene ID:NG_008290
Entrez Gene ID:5265
Ensembl ID:ENSG00000197249

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
COPD, RATE OF DECLINE OF LUNG FUNCTION INHMOX1
MMP1
EMPHYSEMA DUE TO AAT DEFICIENCY 

Cytogenetic Location (from UniGene)

Cytogenetic Location:14q32.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:15: 66068531 - 66069687

 Exon Info From UCSC:
NM_001127701
NM_001002236
NM_001127705
NM_001127703
NM_001127704
NM_001127702
NM_001127706
NM_001127707
NM_001127700
NM_000295
NM_001002235

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3859644Full LengthBC011991serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
4644658Full LengthBC015642serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
4733519IncompleteBC070163serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001002235  NP_000286  NP_001002236  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000295 NP_000286 P01009 Serpin
NM_001002235 NP_001002235 P01009 Serpin
NM_001002236 NP_001002236 P01009 Serpin
NM_001127700 NP_001121172    
NM_001127701 NP_001121173    
NM_001127702 NP_001121174    
NM_001127703 NP_001121175    
NM_001127704 NP_001121176    
NM_001127705 NP_001121177    
NM_001127706 NP_001121178    
NM_001127707 NP_001121179    

Related Sequences

 
mRNAGenPeptSwissProt
M26123 AAA51545 P01009
M11465 AAA51546 P01009
K01396 AAB59375 P01009
AF119873 AAF69627 Q9P173
BC011991 AAH11991 P01009
BC015642 AAH15642 P01009
BT019455 AAV38262 P01009
DQ682455 ABG73380 P01009
FJ830375 ACO55054 C1KH65
HQ448245 ADQ32725  
GU727620 ADU87622 E9KL23
AK315637 BAG38005 P01009
V00496 CAA23755 P01009
X01683 CAA25838 P01009
X02920 CAA26677 P01009
X05826 CAA29267  
X17122 CAA34982 Q13747
BX161449 CAD61914 P01009
BX247968 CAD62306 P01009
BX248002 CAD62334 P01009
BX248257 CAD62585 P01009

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens SERPINA1 NP_001121179 R.norvegicus Serpina1 24648   NP_071964 70
M.musculus Serpina1c 20702 Gene Info NP_033271 66
M.musculus Serpina1b 20701 Gene Info NP_033270 65
M.musculus Serpina1d 20703   NP_033272 65
M.musculus Serpina1a 20700 Gene Info NP_033269 65
M.musculus Serpina1e 20704 Gene Info NP_033273 64

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

NCI-Nature Pathway Interaction Database