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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. IFNGR1, interferon gamma receptor 1
Sequence ID:NM_000416
RefSeqGene ID:NG_007394
Entrez Gene ID:3459
Ensembl ID:ENSG00000027697

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
BCG INFECTION, GENERALIZED FAMILIALIFNGR2
IL12B
IL12RB1
STAT1
STAT1
H. PYLORI INFECTIONPTPRZ1
HEPATITIS B VIRUSIFNAR2
IL10RB
MYCOBACTERIUM TUBERCULOSISCCL2
CD209
CISH
CTSZ
IFNG
IRGM
IRGM
MC3R
SLC11A1
SP110
TIRAP

Cytogenetic Location (from UniGene)

Cytogenetic Location:6q23.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:6: 137519017 - 137540485

NM_000416 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
191174137518620137519775
11751302137522017137522144
13031489137524635137524821
14901662137525468137525640
16631835137527272137527444
18361950137528099137528213
19512138137540379137540566

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3950528Full LengthBC005333interferon gamma receptor 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000407  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000416 NP_000407 P15260 IFNGR1

Related Sequences

 
mRNAGenPeptSwissProt
J03143 AAA52731 P15260
BC005333 AAH05333 P15260
AF056979 AAK30623 Q9BY69
BT006814 AAP35460 P15260
EF173879 ABM53152 A1Z2M9
EF535103 ABQ00413 A5HJZ4
AK222803 BAD96523 Q53GX8
AK312674 BAG35556 B2R6Q9
AK294252 BAG57548 B4DFT7
AK297052 BAG59578 B4DLL6

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens IFNGR1 NP_000407 M.musculus Ifngr1 15979 Gene Info NP_034641 54
R.norvegicus Ifngr1 116465   NP_446235 51

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

NCI-Nature Pathway Interaction Database

BioCarta Pathways
Pathway information courtesy of BioCarta