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Gene Info

Gene Information For:Hs. UCHL1, ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
Sequence ID:NM_004181
RefSeqGene ID:NG_012931
Entrez Gene ID:7345
Ensembl ID:ENSG00000154277

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
PARKINSON DISEASEADH1C
DBH
DRD4
FGF20
GBA
MAPT
NDUFV2
NR4A2
SNCAIP
TBP
PARKINSON DISEASE 5 

Cytogenetic Location (from UniGene)

Cytogenetic Location:4p14Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:4: 41259004 - 41264647

NM_004181 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
11294125889741259025
1301414125913141259142
1422704125962541259753
2714214126266341262813
4225074126373141263816
5085554126389241263939
5566224126524141265307
6236814126611941266177
68211234127000341270444

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2822541Full LengthBC000332ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
2823559Full LengthBC005117ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
4106766Full LengthBC006305ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_004172  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_004181 NP_004172 P09936 EC 3.4.19.12 Peptidase_C12

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC000332 AAH00332 P09936 EC 3.4.19.12
BC005117 AAH05117 P09936 EC 3.4.19.12
BC006305 AAH06305 P09936 EC 3.4.19.12
DQ891998 ABM82924    
DQ895188 ABM86114    
AB209038 BAD92275 Q59GS1  
AK315368 BAG37761 B2RD14  
AK054579 BAG51393 A6NLJ7  
X04741 CAA28443 P09936 EC 3.4.19.12

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens UCHL1 NP_004172 M.musculus Uchl1 22223 Gene Info NP_035800 96
R.norvegicus Uchl1 29545   NP_058933 96

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

NCI-Nature Pathway Interaction Database