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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. STK11, Serine/threonine kinase 11
Sequence ID:NM_000455
RefSeqGene ID:NG_007460
Entrez Gene ID:6794
Ensembl ID:ENSG00000118046

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
GERM CELL TUMORSBCL10
FGFR3
KIT
PEUTZ-JEGHERS SYNDROME 

Cytogenetic Location (from UniGene)

Cytogenetic Location:19p13.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:19: 1206574 - 1228093

NM_000455 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
1140512057971207201
1406148912184151218498
1490157912193221219411
1580171212203711220503
1713184912205791220715
1850197712212111221338
1978203512219471222004
2036222312229831223170
2224243312264521226661
2434327612275911228433

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3689780Full LengthBC007981serine/threonine kinase 11
3946005Full LengthBC019334serine/threonine kinase 11

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000446  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000455 NP_000446 Q15831 EC 2.7.11.1 Pkinase

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U63333 AAB05809 Q15831 EC 2.7.11.1
AF035625 AAC39527 Q15831 EC 2.7.11.1
AF217978 AAG17221 Q9HBS3  
BC007981 AAH07981 Q15831 EC 2.7.11.1
BC019334 AAH19334 Q15831 EC 2.7.11.1
DQ893232 ABM84158    
DQ896561 ABM87560    
EF644172 ABR45718 A6YR18  
AB209553 BAD92790 Q59FA7  
AK314858 BAG37374 Q15831 EC 2.7.11.1
AJ844634 CAH59749 Q5ZEZ1  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens STK11 NP_000446 M.musculus Stk11 20869 Gene Info NP_035622 91
R.norvegicus Stk11 314621   NP_001101539 91
D.melanogaster lkb1 41673   NP_001163606 55
C.elegans par-4 180185   NP_507533 41

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

NCI-Nature Pathway Interaction Database