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Gene Info

Gene Information For:Hs. FUS, Fused in sarcoma
Sequence ID:NM_004960
NM_001170634
NM_001170937
RefSeqGene ID:NG_012889
Entrez Gene ID:2521
Ensembl ID:ENSG00000089280

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, placenta, pooled tissue, prostate, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
AMYOTROPHIC LATERAL SCLEROSIS 6, AUTOSOMAL RECESSIVE, WITH OR WITHOUTFRONTOTEMPORAL DEMENTIA 
TREMOR, HEREDITARY ESSENTIAL, 4 

Cytogenetic Location (from UniGene)

Cytogenetic Location:16p11.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:16: 31201695 - 31202164

 Exon Info From UCSC:
NM_004960
NM_001170634
NM_001170937

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2822692Full LengthBC000402fusion (involved in t(12;16) in malignant liposarcoma)
3345294Full LengthBC002459fusion (involved in t(12;16) in malignant liposarcoma)
3937437Full LengthBC026062fusion (involved in t(12;16) in malignant liposarcoma)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_004951  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001170634 NP_001164105    
NM_001170937 NP_001164408    
NM_004960 NP_004951 Q6IBQ5
P35637
RRM_1
zf-RanBP

Related Sequences

 
mRNAGenPeptSwissProt
U36561 AAA79948 Q13344
S62140 AAB27102 Q6IBQ5
P35637
BC000402 AAH00402 Q6IBQ5
P35637
BC002459 AAH02459 Q6IBQ5
P35637
BC026062 AAH26062 Q8TBR3
BT007131 AAP35795 Q6IBQ5
P35637
DQ891705 ABM82631  
DQ894882 ABM85808  
AB208902 BAD92139 Q59H57
AK290936 BAF83625 A8K4H1
AK299129 BAG61182 B4DR70
AK301110 BAG62709 B4DVJ7
X71428 CAA50559 P35637
CR456747 CAG33028 Q6IBQ5
P35637

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens FUS NP_001164408 M.musculus Fus 233908 Gene Info NP_631888 98
R.norvegicus Fus 317385   NP_001012137 97
D.melanogaster caz 32587   NP_523365 53
A.gambiae AgaP_AGAP001645 1281527   XP_321451 53
C.elegans C27H5.3 174175   NP_495483 46
A.thaliana TAF15b 835960   NP_851215 40

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)