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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. CDH1, cadherin 1, type 1, E-cadherin (epithelial)
Sequence ID:NM_004360
RefSeqGene ID:NG_008021
Entrez Gene ID:999
Ensembl ID:ENSG00000039068

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
ADENOCARCINOMA, OVARIAN, SOMATICAKT1
CTNNB1
OPCML
PARK2
PIK3CA
PIK3CA
BREAST CANCERAKT1
ATM
BARD1
BRCA1
BRCA2
BRIP1
CASP8
CHEK2
CHEK2
HMMR
KRAS
NQO2
NQO2
PALB2
PHB
PIK3CA
PIK3CA
PPM1D
RAD51
RAD54L
RB1CC1
SLC22A18
TP53
TP53
TSG101
XRCC3
XRCC3
ENDOMETRIAL CANCERMLH3
MSH6
PTEN
GASTRIC CANCER RISK AFTER H. PYLORI INFECTIONAPC
APC
CASP10
ERBB2
FGFR2
IL1B
IL1RN
IRF1
KLF6
KLF6
KRAS
MUTYH
PIK3CA
PIK3CA
PROSTATE CANCERAR
BRCA2
CD82
CHEK2
CHEK2
ELAC2
HIP1
HIP1
HNF1B
KLF6
KLF6
MAD1L1
MSR1
MXI1
MXI1
PTEN
TUSC3
TUSC3
ZFHX3

Cytogenetic Location (from UniGene)

Cytogenetic Location:16q22.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:16: 68771254 - 68867439

 Exon Info From UCSC:
NM_004360

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
40148047Full LengthBC146662cadherin 1, type 1, E-cadherin (epithelial)
40148986Full LengthBC141838cadherin 1, type 1, E-cadherin (epithelial)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_004351  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_004360 NP_004351 P12830 Cadherin
Cadherin_C

Related Sequences

 
mRNAGenPeptSwissProt
L08599 AAA61259 P12830
BC141838 AAI41839 A5D8W4
BC146662 AAI46663 A5D8W4
EU709494 ACD87624 B3GN61
AB025105 BAA88956 Q9UII8
AB025106 BAA88957 Q9UII7
AK290012 BAF82701 P12830
AK312551 BAG35448 P12830
AK297913 BAG60232 B4DNH0
X12790 CAA31279 P12830
X52279 CAA36522 P12830
Z13009 CAA78353 P12830
Z18923 CAA79356 P12830

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens CDH1 NP_004351 M.musculus Cdh1 12550 Gene Info NP_033994 81
R.norvegicus Cdh1 83502   NP_112624 81

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

NCI-Nature Pathway Interaction Database

BioCarta Pathways
Pathway information courtesy of BioCarta