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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. PRSS1, Protease, serine, 1 (trypsin 1)
Sequence ID:NM_002769
RefSeqGene ID:NG_001333
Entrez Gene ID:5644
Ensembl ID:ENSG00000204983

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssemblies

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
PANCREATITIS, CHRONIC, PROTECTION AGAINSTCFTR
CFTR
CFTR
CTRC
PRSS2
PRSS2
SPINK1

Cytogenetic Location (from UniGene)

Cytogenetic Location:7q34Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:7: 142457324 - 142460871

NM_002769 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
157142457318142457374
58217142458405142458564
218471142459624142459877
472608142460281142460417
609817142460718142460926

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
40022561Full LengthBC103998protease, serine, 1 (trypsin 1)
40114572Full LengthBC128226protease, serine, 1 (trypsin 1)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002760  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_002769 NP_002760 P07477 EC 3.4.21.4 Trypsin
NM_002770 NP_002761 Q5NV56
P07478
EC 3.4.21.4 Trypsin

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M22612 AAA61231 P07477 EC 3.4.21.4
M27602 AAA61232 Q5NV56
P07478
EC 3.4.21.4
BC005814 AAH05814 Q6PK75  
BC103997 AAI03998 Q3SY20  
BC103998 AAI03999 Q3SY19  
BC107784 AAI07785 Q5NV56
P07478
EC 3.4.21.4
BC128226 AAI28227 P07477 EC 3.4.21.4
AY052784 AAL14244 Q7Z5F3  
DQ778083 ABI63347 A6XGL3  
DQ846872 ABI63359 A6XMV8  
DQ846873 ABI63360 A6XMV9  
DQ891044 ABM81970    
DQ894223 ABM85149    
AK312199 BAG35132 P07477 EC 3.4.21.4
AK293375 BAG56887 B4DDX6  
XM_003960942 XP_003960991    
XM_003960943 XP_003960992    
XM_003960944 XP_003960993    

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PRSS1 NP_002760 M.musculus 2210010C04Rik 67373 Gene Info NP_075822 76
R.norvegicus Prss3 286911   NP_775150 76
D.melanogaster alphaTry 48316   NP_476771 41
D.melanogaster thetaTry 36218   NP_523693 41
D.melanogaster betaTry 47901   NP_524904 40
D.melanogaster Ser8 36489   NP_610874 39
D.melanogaster CG30025 246398   NP_725036 39
D.melanogaster CG17571 35409   NP_610109 39
D.melanogaster gammaTry 36221   NP_725034 39
D.melanogaster CG30031 246404   NP_725035 39
D.melanogaster deltaTry 48343   NP_523694 39
D.melanogaster epsilonTry 49080   NP_525112 38
D.melanogaster CG17239 59224   NP_722784 38
D.melanogaster Ser12 33406   NP_523456 37
D.melanogaster iotaTry 36223   NP_523695 33

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)