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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. ERBB2, v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
Sequence ID:NM_001005862
NM_004448
RefSeqGene ID:NG_007503
Entrez Gene ID:2064
Ensembl ID:ENSG00000141736

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
ADENOCARCINOMA OF LUNG, RESPONSE TO TYROSINE KINASE INHIBITOR INBRAF
CASP8
CYP2A6
DLEC1
EGFR
ERCC6
FASLG
IRF1
KRAS
MAP3K8
MAP3K8
PARK2
PIK3CA
PIK3CA
PPP2R1B
RASSF1
SLC22A18
GASTRIC CANCER RISK AFTER H. PYLORI INFECTIONAPC
APC
CASP10
CDH1
FGFR2
IL1B
IL1RN
IRF1
KLF6
KLF6
KRAS
MUTYH
PIK3CA
PIK3CA
GLIOBLASTOMABRCA2
DMBT1
LGI1
MSH2
PPARG
PTEN
WDR11

Cytogenetic Location (from UniGene)

Cytogenetic Location:17q12Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:17: 37844353 - 37851434

 Exon Info From UCSC:
NM_001005862
NM_004448

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
100013444Full LengthBC167147v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
100062227Full LengthBC156755v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
6178526IncompleteBC080193v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001005862  NP_004439  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001005862 NP_001005862     Pkinase
Furin-like
Recep_L_domain
Pkinase_Tyr
NM_004448 NP_004439 P04626 EC 2.7.10.1 Furin-like
Recep_L_domain
Pkinase_Tyr

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M11730 AAA75493 P04626 EC 2.7.10.1
AF177761 AAD56009 Q9UK79  
BC156755 AAI56756    
BC167147 AAI67147 P04626 EC 2.7.10.1
HM437238 ADN43069 E2I6F8  
AK295195 BAG58195 P04626 EC 2.7.10.1
AK296908 BAG59464 B4DLA2  
AK300321 BAG62073 B4DTR1  
X03363 CAA27060 P04626 EC 2.7.10.1

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens ERBB2 NP_004439 M.musculus Erbb2 13866 Gene Info NP_001003817 88
R.norvegicus Erbb2 24337   NP_058699 88

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

NCI-Nature Pathway Interaction Database

BioCarta Pathways
Pathway information courtesy of BioCarta