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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. LDHB, Lactate dehydrogenase B
Sequence ID:NM_001174097
NM_002300
RefSeqGene ID:NG_017038
Entrez Gene ID:3945
Ensembl ID:ENSG00000111716

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
LACTATE DEHYDROGENASE-B DEFICIENCY 

Cytogenetic Location (from UniGene)

Cytogenetic Location:12p12.2-p12.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:12: 21788275 - 21810740

 Exon Info From UCSC:
NM_001174097
NM_002300

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2961445Full LengthBC002362lactate dehydrogenase B
3685985Full LengthBC015122lactate dehydrogenase B
4902461Full LengthBC071860lactate dehydrogenase B

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002291  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001174097 NP_001167568      
NM_002300 NP_002291 Q5U077
P07195
EC 1.1.1.27 Ldh_1_N
Ldh_1_C

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC002362 AAH02362 Q5U077
P07195
EC 1.1.1.27
BC015122 AAH15122 Q5U077
P07195
EC 1.1.1.27
BC071860 AAH71860 Q5U077
P07195
EC 1.1.1.27
AY189689 AAO85222 Q5U077
P07195
EC 1.1.1.27
BT019764 AAV38569 Q5U077
P07195
EC 1.1.1.27
BT019765 AAV38570 Q5U077
P07195
EC 1.1.1.27
DQ891854 ABM82780    
D28368 BAA05734    
AB209231 BAD92468 Q59G78  
AK312328 BAG35250 Q5U077  
Y00711 CAA68701 Q5U077
P07195
EC 1.1.1.27

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens LDHB NP_001167568 M.musculus Gm5514 433229 Gene Info XP_904967 97

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)