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Gene Info

Gene Information For:Hs. IRF1, interferon regulatory factor 1
Sequence ID:NM_002198
RefSeqGene ID:NG_011450
Entrez Gene ID:3659
Ensembl ID:ENSG00000125347

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
ADENOCARCINOMA OF LUNG, RESPONSE TO TYROSINE KINASE INHIBITOR INBRAF
CASP8
CYP2A6
DLEC1
EGFR
ERBB2
ERCC6
FASLG
KRAS
MAP3K8
MAP3K8
PARK2
PIK3CA
PIK3CA
PPP2R1B
RASSF1
SLC22A18
GASTRIC CANCER RISK AFTER H. PYLORI INFECTIONAPC
APC
CASP10
CDH1
ERBB2
FGFR2
IL1B
IL1RN
KLF6
KLF6
KRAS
MUTYH
PIK3CA
PIK3CA
MACROCYTIC ANEMIA, REFRACTORY, DUE TO 5Q DELETION, SOMATICRPS14

Cytogenetic Location (from UniGene)

Cytogenetic Location:5q31.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:5: 131821322 - 131825170

NM_002198 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
142480131817300131819766
24812616131820053131820188
26172666131821358131821407
26672789131821942131822064
27902919131822248131822377
29202969131822486131822535
29703146131822645131822821
31473246131823617131823716
32473338131825083131825174
33393567131826236131826464

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3623414Full LengthBC009483interferon regulatory factor 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002189  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_002198 NP_002189 Q6FHN8
P10914
IRF

Related Sequences

 
mRNAGenPeptSwissProt
BC009483 AAH09483 Q6FHN8
P10914
BT019755 AAV38560 Q6FHN8
P10914
BT019756 AAV38561 Q6FHN8
P10914
DQ893269 ABM84195  
DQ896599 ABM87598  
AB103081 BAD89424 Q5FBX3
AB209624 BAD92861 Q59F37
AK314025 BAG36735 Q6FHN8
AK298770 BAG60912 B4DQF0
X14454 CAA32624 Q6FHN8
P10914
CR541713 CAG46514 Q6FHN8
P10914

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens IRF1 NP_002189 M.musculus Irf1 16362 Gene Info NP_001152868 86
R.norvegicus Irf1 24508   NP_036723 85

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

NCI-Nature Pathway Interaction Database

BioCarta Pathways
Pathway information courtesy of BioCarta