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Gene Info

Gene Information For:Hs. HLA-DQB1, Major histocompatibility complex, class II, DQ beta 1
Sequence ID:NM_001243961
NM_002123
NM_001243962
RefSeqGene ID:NG_029922
Entrez Gene ID:3119
Ensembl ID:ENSG00000179344

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
CELIAC DISEASEHLA-DQA1
HLA-DQA1
CREUTZFELDT-JAKOB DISEASEPRNP
PRNP
PRNP
DIABETES MELLITUS, INSULIN-DEPENDENTFOXP3
HNF1A
ITPR3
OAS1
PTPN22
SH2B3
MULTIPLE SCLEROSISCD24
CIITA
HLA-DRB1
HLA-DRB1
HLA-DRB1
IL7R
PDCD1
PTPRC

Cytogenetic Location (from UniGene)

Cytogenetic Location:6p21.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:6: 32629122 - 32634377

Transcript StartTranscript EndChromosomal Start Chromosomal End
183873262765632628025
3884983262912332629233
4997803262974332630024
78110503263257432632843
105112413263427532634465

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4574913Full LengthBC012106major histocompatibility complex, class II, DQ beta 1
40127514IncompleteBC128595major histocompatibility complex, class II, DQ beta 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002114  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001243961 NP_001230890    
NM_001243962 NP_001230891    
NM_002123 NP_002114 Q5Y7D3 ig
MHC_II_beta
C1-set

Related Sequences

 
mRNAGenPeptSwissProt
M24364 AAA36236 Q29967
M35982 AAA36251 Q30007
M14189 AAA36268 P01920
M17955 AAA36269 Q30091
M26042 AAA36270 P01920
M19239 AAA52319 Q29785
M33907 AAA52672 P01920
M25325 AAA59675 Q29965
M25326 AAA59676 O78219
M25327 AAA59677 P01920
M17206 AAA59696 Q30092
M17207 AAA59697 P01920
M17204 AAA59698 Q30100
M60028 AAA59755 P01920
M35730 AAA59763 Q30090
M17563 AAA59764 Q30093
M17564 AAA59765 Q5Y7F1
P01920
M17565 AAA59766 O19709
M21135 AAA59767 O19710
M32577 AAA59768 O19714
O19711
M20432 AAA59769 P01920
Q5Y7D6
M16996 AAA59770 P01920
M81140 AAA59771 Q30096
M81141 AAA59772 Q30099
M20505 AAA59773 O19714
O19711
J00198 AAA59788 Q30132
M25024 AAA59792 Q30133
Q29900
M25025 AAA59793 P01920
M13279 AAA59807 Q30146
M22549 AAA59820 Q30153
M22550 AAA59821 O19741
M16276 AAA59823 Q30155
M57650 AAA63216 Q29969
M57649 AAA63217 Q29970
M59801 AAA64234 Q30088
M59800 AAA64235 P01920
L42626 AAA85335 P01920
L40180 AAA92331 Q30097
L40181 AAA92332 Q30098
U63321 AAB05807 Q9TQ76
Q30202
U83582 AAB41231 P01920
U66400 AAB51698 P01920
AF000447 AAB86436 O19506
U83585 AAC02814 O19764
L34095 AAC41963 Q30074
L34096 AAC41964 P01920
L34097 AAC41965 O19707
L34098 AAC41966 P01920
L34099 AAC41967 Q30077
L34100 AAC41968 Q30078
L34101 AAC41969 P01920
L34102 AAC41970 Q30079
L34103 AAC41971 P01920
L34104 AAC41972 P01920
L34105 AAC41973 P01920
L34106 AAC41974 P01920
L34107 AAC41975 P01920
L40179 AAC41976 O19712
S79787 AAD14316 Q29755
AF113250 AAD17203 Q9TQ76
Q30202
AF195245 AAF28315 P01920
BC012106 AAH12106 Q5Y7F6
P01920
BC128595 AAI28596 A2VCT9
AF291674 AAK91824 Q95IH2
AY656681 AAV71028 P01920
AY656682 AAV71029 P01920
AY656683 AAV71030 P01920
DQ136036 AAZ67362 Q45FY0
DQ892298 ABM83224  
DQ895497 ABM86423  
AB209580 BAD92817 Q59F80
AB209638 BAD92875 Q59F23
AK295255 BAG58244 B4DHT2
AK295476 BAG58403 B4DI91
AK295695 BAG58545 B4DIN3
AK296613 BAG59223 Q5Y7A9
AK304543 BAG65340 B4E328
AK316333 BAH14704 Q5Y7D6
V00529 CAA23788 Q30133
Q29900
X03068 CAA26872 Q5Y7F1
P01920
X96420 CAA65280 P01920

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens HLA-DQB1 NP_002114 R.norvegicus RT1-Bb 309622   NP_001004084 77
M.musculus H2-Ab1 14961 Gene Info NP_996988 75

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)