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Gene Info

Gene Information For:Hs. RB1, retinoblastoma 1
Sequence ID:NM_000321
RefSeqGene ID:NG_009009
Entrez Gene ID:5925
Ensembl ID:ENSG00000139687

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
BLADDER CANCER, SOMATICFGFR3
HRAS
KRAS
LOC100270680
TACC3
OSTEOSARCOMACHEK2
CHEK2
TNFRSF11A
TNFRSF11A
TP53
TP53
RETINOBLASTOMA 
SMALL CELL CANCER OF THE LUNG, SOMATIC 

Cytogenetic Location (from UniGene)

Cytogenetic Location:13q14.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:13: 48877951 - 49054640

 Exon Info From UCSC:
NM_000321

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5142020Full LengthBC039060retinoblastoma 1
5267622Full LengthBC040540retinoblastoma 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000312  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000321 NP_000312 P06400 RB_B
RB_A

Related Sequences

 
mRNAGenPeptSwissProt
M19701 AAA60259 Q92728
M33647 AAA69806 P06400
M15400 AAA69807 P06400
M28419 AAA69808 P06400
L41870 AAB59465 P06400
AF043224 AAC26845  
BC039060 AAH39060 P06400
BC040540 AAH40540 P06400
DQ891564 ABM82490  
DQ894752 ABM85678  
AB208788 BAD92025 Q59HH0
AK291258 BAF83947 P06400
AK299179 BAG61225 B4DRB3
AK300284 BAG62042 B4DTN0

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens RB1 NP_000312 M.musculus Rb1 19645 Gene Info NP_033055 91
R.norvegicus Rb1 24708   NP_058741 90

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

NCI-Nature Pathway Interaction Database

BioCarta Pathways
Pathway information courtesy of BioCarta