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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. PINK1, PTEN induced putative kinase 1
Sequence ID:NM_032409
RefSeqGene ID:NG_008164
Entrez Gene ID:65018
Ensembl ID:ENSG00000158828

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
PARKINSON DISEASE 6, EARLY ONSET 

Cytogenetic Location (from UniGene)

Cytogenetic Location:1p36Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 20959947 - 20978004

NM_032409 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
14812095994720960427
4827692096433420964621
7708702096638420966484
87110532097098220971164
105412172097205220972215
121813452097499720975124
134615822097548720975723
158326592097692620978002

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5214483Full LengthBC028215PTEN induced putative kinase 1
3891886IncompleteBC009534PTEN induced putative kinase 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_115785  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_032409 NP_115785 Q9BXM7 EC 2.7.11.1 Pkinase

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC009534 AAH09534 Q9BXM7 EC 2.7.11.1
BC028215 AAH28215 Q9BXM7 EC 2.7.11.1
AF316873 AAK28062 Q9BXM7 EC 2.7.11.1
DQ891033 ABM81959    
DQ893330 ABM84256    
DQ894212 ABM85138    
DQ896646 ABM87645    
AB053323 BAB55647 Q9BXM7 EC 2.7.11.1
AK075225 BAC11484 Q9BXM7 EC 2.7.11.1

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PINK1 NP_115785 M.musculus Pink1 68943 Gene Info NP_081156 82
R.norvegicus Pink1 298575   NP_001100164 79
C.elegans pink-1 173918   NP_495017 36

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)