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Gene Info

Gene Information For:Hs. ITGB2, integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
Sequence ID:NM_000211
NM_001127491
RefSeqGene ID:NG_007270
Entrez Gene ID:3689
Ensembl ID:ENSG00000160255

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssemblies

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
LEUKOCYTE ADHESION DEFICIENCY 

Cytogenetic Location (from UniGene)

Cytogenetic Location:21q22.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:21: 46305905 - 46348753

 Exon Info From UCSC:
NM_000211
NM_001127491

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3532902Full LengthBC005861integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
3532854IncompleteBC021077integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000202  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000211 NP_000202 P05107 Integrin_beta
Integrin_B_tail
EGF_2
NM_001127491 NP_001120963    

Related Sequences

 
mRNAGenPeptSwissProt
M15395 AAA59490 P05107
S81234 AAB21404 P05107
BC005861 AAH05861 P05107
BC021077 AAH21077 Q6PJ75
L78790 AAL40068 Q8WWJ8
DQ892684 ABM83610  
DQ895927 ABM86853  
EU832689 ACE87021  
EU832617 ACE87708  
AB208909 BAD92146 Q59H50
AK222505 BAD96225 P05107
AK095992 BAG53190 P05107
AK303488 BAG64523 B4E0R1
Y00057 CAA68266 P05107

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens ITGB2 NP_000202 M.musculus Itgb2 16414 Gene Info NP_032430 82
R.norvegicus Itgb2 309684   NP_001032869 81

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

NCI-Nature Pathway Interaction Database

BioCarta Pathways
Pathway information courtesy of BioCarta