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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. HK1, Hexokinase 1
Sequence ID:NM_033500
NM_033498
NM_033497
NM_000188
NM_033496
RefSeqGene ID:NG_012077
Entrez Gene ID:3098
Ensembl ID:ENSG00000156515

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, skin, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
HEMOLYTIC ANEMIA DUE TO HEXOKINASE DEFICIENCY 

Cytogenetic Location (from UniGene)

Cytogenetic Location:10q22Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:10: 71078606 - 71161635

 Exon Info From UCSC:
NM_033500
NM_033498
NM_033497
NM_000188
NM_033496

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3163058Full LengthBC008730hexokinase 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000179  NP_277032  NP_277031  NP_277035  NP_277033  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000188 NP_000179 P19367 EC 2.7.1.1 Hexokinase_1
Hexokinase_2
NM_033496 NP_277031     Hexokinase_1
Hexokinase_2
NM_033497 NP_277032     Hexokinase_1
Hexokinase_2
NM_033498 NP_277033     Hexokinase_1
Hexokinase_2
NM_033500 NP_277035     Hexokinase_1
Hexokinase_2

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M75126 AAA52646 P19367 EC 2.7.1.1
U38226 AAB40527 P78542  
U38227 AAB40528 P78542  
U38228 AAB40529 Q99609  
AF073786 AAC25424 P19367 EC 2.7.1.1
BC008730 AAH08730 P19367 EC 2.7.1.1
DQ893281 ABM84207    
DQ896762 ABM87761    
AB209526 BAD92763 Q59FD4  
AK292012 BAF84701 A8K7J7  
AK091267 BAG52321 B3KRA9  
AK128226 BAG54651 B3KXY9  
AK294428 BAG57673 B4DG62  
X66957 CAA47379 P19367 EC 2.7.1.1

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens HK1 NP_000179 M.musculus Hk1 15275 Gene Info NP_001139572 93
D.melanogaster Hex-t2 43191   NP_733151 45
S.pombe hxk1 2542634   NP_592948 38
N.crassa NCU02542 3881807   XP_965673 38
S.cerevisiae HXK2 852639   NP_011261 38
S.cerevisiae HXK1 850614   NP_116711 36

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

NCI-Nature Pathway Interaction Database

BioCarta Pathways
Pathway information courtesy of BioCarta