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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. TGFBI, Transforming growth factor, beta-induced, 68kDa
Sequence ID:NM_000358
RefSeqGene ID:NG_012646
Entrez Gene ID:7045
Ensembl ID:ENSG00000120708

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
CORNEAL DYSTROPHY, AVELLINO TYPE 
CORNEAL DYSTROPHY, EPITHELIAL BASEMENT MEMBRANE 
CORNEAL DYSTROPHY, GROENOUW TYPE I 
CORNEAL DYSTROPHY, LATTICE TYPEIIIA 
CORNEAL DYSTROPHY, REIS-BUCKLERS TYPE 
CORNEAL DYSTROPHY, THIEL-BEHNKE TYPE 
CORNEAL DYSTROPHY,LATTICE TYPE I 

Cytogenetic Location (from UniGene)

Cytogenetic Location:5q31Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:5: 135364679 - 135399506

 Exon Info From UCSC:
NM_000358

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2958878Full LengthBC004972transforming growth factor, beta-induced, 68kDa
3506051Full LengthBC000097transforming growth factor, beta-induced, 68kDa

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000349  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000358 NP_000349 Q15582 Fasciclin
EMI

Related Sequences

 
mRNAGenPeptSwissProt
M77349 AAA61163 Q15582
BC000097 AAH00097 Q15582
BC004972 AAH04972 Q15582
BT009820 AAP88822 Q15582
DQ892178 ABM83104  
EU176690 ABW03491  
AB209598 BAD92835 Q59F63
AK222833 BAD96553 Q53GU8
AK093916 BAG52785  
AK094055 BAG52805  
AK094581 BAG52893  
AK298603 BAG60787  
AK303643 BAH14005  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens TGFBI NP_000349 M.musculus Tgfbi 21810 Gene Info NP_033395 91
R.norvegicus Tgfbi 116487   NP_446254 90

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

NCI-Nature Pathway Interaction Database