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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. LTA, lymphotoxin alpha (TNF superfamily, member 1)
Sequence ID:NM_000595
NM_001159740
RefSeqGene ID:NG_012010
Entrez Gene ID:4049
Ensembl ID:ENSG00000226979

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
LEPROSY 
MYOCARDIAL INFARCTIONESR1
F13A1
F7
GCLC
GCLM
ITGB3
LGALS2
LRP8
MIAT
OLR1
PSMA6
THBD
TNFSF4
PSORIATIC ARTHRITISNOD2

Cytogenetic Location (from UniGene)

Cytogenetic Location:6p21.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:6: 31540513 - 31542100

 Exon Info From UCSC:
NM_000595
NM_001159740

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4341621Full LengthBC034729lymphotoxin alpha (TNF superfamily, member 1)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000586  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000595 NP_000586 Q5STV3
P01374
TNF
NM_001159740 NP_001153212    

Related Sequences

 
mRNAGenPeptSwissProt
BC034729 AAH34729 Q6FG55
P01374
DQ123821 AAZ32914 Q45NE9
DQ123822 AAZ32915 Q45NE8
DQ123823 AAZ32916 Q45NE7
DQ123824 AAZ32917 Q45NE6
DQ123825 AAZ32918 Q45NE5
DQ123826 AAZ32919 Q45NE4
DQ123827 AAZ32920 Q45NE3
DQ891119 ABM82045  
DQ894298 ABM85224  
D00102 BAA00064 Q5ST95
P01374
D12614 BAA02139 Q5STV3
P01374
A06316 CAA00536 Q5STV3
P01374
X01393 CAA25649 Q5STV3
P01374
CR542253 CAG47049 Q6FG55
CR542273 CAG47069 Q6FG55

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens LTA NP_000586 R.norvegicus Lta 25008   NP_542947 74
M.musculus Lta 16992 Gene Info NP_034865 73

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

NCI-Nature Pathway Interaction Database