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Gene Info

Gene Information For:Hs. SDHD, Succinate dehydrogenase complex, subunit D, integral membrane protein
Sequence ID:NM_003002
RefSeqGene ID:NG_012337
Entrez Gene ID:6392
Ensembl ID:ENSG00000204370

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, stem cell, stomach, t-cell, testis, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
CARCINOID TUMORS, INTESTINAL 
COWDEN-LIKE SYNDROMESDHB
PARAGANGLIOMA AND GASTRIC STROMAL SARCOMASDHB
SDHC
PARAGANGLIOMAS 1, WITH OR WITHOUT DEAFNESS 
PHEOCHROMOCYTOMAGDNF
KIF1B
MAX
RET
SDHB
TMEM127
TMEM127
VHL

Cytogenetic Location (from UniGene)

Cytogenetic Location:11q23Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:11: 111957621 - 111966517

NM_003002 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
1113111957570111957682
114230111958580111958696
231375111959590111959734
3761364111965528111966516

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3930691Full LengthBC005263succinate dehydrogenase complex, subunit D, integral membrane protein
4063808Full LengthBC009574succinate dehydrogenase complex, subunit D, integral membrane protein
4108104Full LengthBC012603succinate dehydrogenase complex, subunit D, integral membrane protein
4275516Full LengthBC022350succinate dehydrogenase complex, subunit D, integral membrane protein
4277540Full LengthBC070307succinate dehydrogenase complex, subunit D, integral membrane protein
4279214Full LengthBC015188succinate dehydrogenase complex, subunit D, integral membrane protein
4292983Full LengthBC015992succinate dehydrogenase complex, subunit D, integral membrane protein
4774525Full LengthBC071755succinate dehydrogenase complex, subunit D, integral membrane protein
6450992Full LengthBC071756succinate dehydrogenase complex, subunit D, integral membrane protein

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002993  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_003002 NP_002993 O14521 CybS

Related Sequences

 
mRNAGenPeptSwissProt
BC005263 AAH05263 O14521
BC009574 AAH09574 O14521
BC012603 AAH12603 O14521
BC015188 AAH15188 O14521
BC015992 AAH15992 O14521
BC022350 AAH22350 O14521
BC070307 AAH70307 O14521
BC071755 AAH71755 O14521
BC071756 AAH71756 O14521
BT007238 AAP35902 O14521
DQ892701 ABM83627  
DQ896292 ABM87291  
AB006202 BAA22054 O14521
AK075360 BAG52120 O14521
CR456932 CAG33213 O14521

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens SDHD NP_002993 M.musculus Sdhd 66925 Gene Info NP_080124 82
R.norvegicus Sdhd 363061   NP_942083 81
A.gambiae AgaP_AGAP000618 1271698   XP_310463 41
D.melanogaster CG10219 42808   NP_651181 37

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta