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Gene Info

Gene Information For:Hs. RET, ret proto-oncogene
Sequence ID:NM_020630
NM_020975
NM_000323
NM_020629
RefSeqGene ID:NG_007489
Entrez Gene ID:5979
Ensembl ID:ENSG00000165731

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
CENTRAL HYPOVENTILATION SYNDROMEASCL1
BDNF
EDN3
GDNF
PHOX2B
HIRSCHSPRUNG DISEASEEDN3
GDNF
L1CAM
NRTN
PHOX2B
MEDULLARY THYROID CARCINOMA, FAMILIALNTRK1
MULTIPLE ENDOCRINE NEOPLASIA IIA 
MULTIPLE ENDOCRINE NEOPLASIA IIB 
PHEOCHROMOCYTOMAGDNF
KIF1B
MAX
SDHB
SDHD
TMEM127
TMEM127
VHL
RENAL ADYSPLASIAUPK3A

Cytogenetic Location (from UniGene)

Cytogenetic Location:10q11.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:10: 43612031 - 43623717

 Exon Info From UCSC:
NM_020630
NM_020975

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3160389Full LengthBC004257ret proto-oncogene

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_066124  NP_065681  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_020630 NP_065681     Cadherin
Pkinase
Pkinase_Tyr
NM_020975 NP_066124 P07949 EC 2.7.10.1 Cadherin
Pkinase_Tyr

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC003072 AAH03072 Q9BTX6  
BC004257 AAH04257 P07949 EC 2.7.10.1
AK291807 BAF84496 P07949 EC 2.7.10.1
AK294827 BAG57939 B4DGX8  
X15262 CAA33333 P07949 EC 2.7.10.1
Y12528 CAA73131 Q9UQV8  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens RET NP_066124 R.norvegicus Ret 24716   NP_036775 85
M.musculus Ret 19713 Gene Info NP_033076 83

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

NCI-Nature Pathway Interaction Database