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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. APRT, Adenine phosphoribosyltransferase
Sequence ID:NM_000485
NM_001030018
RefSeqGene ID:NG_008013
Entrez Gene ID:353
Ensembl ID:ENSG00000198931

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
ADENINE PHOSPHORIBOSYLTRANSFERASE DEFICIENCY 

Cytogenetic Location (from UniGene)

Cytogenetic Location:16q24Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:16: 88875999 - 88878331

 Exon Info From UCSC:
NM_000485
NM_001030018

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
40032160Full LengthBC107151adenine phosphoribosyltransferase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001025189  NP_000476  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000485 NP_000476 P07741 EC 2.4.2.7 Pribosyltran
NM_001030018 NP_001025189     Pribosyltran

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC107151 AAI07152 P07741 EC 2.4.2.7
CR749423 CAH18261 P07741 EC 2.4.2.7

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens APRT NP_000476 R.norvegicus Aprt 292072   NP_001013079 87
M.musculus Aprt 11821 Gene Info NP_033828 83
D.melanogaster Aprt 48224   NP_476637 48
N.crassa NCU02090 3879876   XP_963727 47
S.cerevisiae APT1 854986   NP_013690 47
C.elegans T19B4.3 172232   NP_491663 46
S.pombe apt1 2542022   NP_594433 45
A.gambiae AgaP_AGAP005723 1276396   XP_315739 42
A.thaliana APT1 839636   NP_564284 42

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)