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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. LDHA, Lactate dehydrogenase A
Sequence ID:NM_001165414
NM_005566
NM_001165416
NM_001135239
NM_001165415
RefSeqGene ID:NG_008185
Entrez Gene ID:3939
Ensembl ID:ENSG00000134333

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssemblies

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
GLYCOGEN STORAGE DISEASE XI 

Cytogenetic Location (from UniGene)

Cytogenetic Location:11p15.4Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:11: 18416109 - 18429394

 Exon Info From UCSC:
NM_001165414
NM_005566
NM_001165416
NM_001135239
NM_001165415

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4096518Full LengthBC067223lactate dehydrogenase A

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_005557  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001135239 NP_001128711      
NM_001165414 NP_001158886      
NM_001165415 NP_001158887      
NM_001165416 NP_001158888      
NM_005566 NP_005557 P00338 EC 1.1.1.27 Ldh_1_N
Ldh_1_C

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC067223 AAH67223 P00338 EC 1.1.1.27
AY423727 AAS00490 P00338 EC 1.1.1.27
AK130587 BAC85389 P00338 EC 1.1.1.27
AK223078 BAD96798 P00338 EC 1.1.1.27
AK296089 BAG58843 B4DJI1  
AK296667 BAG59264 P00338 EC 1.1.1.27
AK298834 BAH12879 P00338 EC 1.1.1.27
X02152 CAA26088 P00338 EC 1.1.1.27
CR456775 CAG33056 P00338 EC 1.1.1.27
CR541714 CAG46515 P00338 EC 1.1.1.27

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens LDHA NP_001158886 R.norvegicus Ldha 24533   NP_058721 94
M.musculus Ldha 16828 Gene Info NP_001129541 91
A.gambiae AgaP_AGAP004880 1275079   XP_314306 60
D.melanogaster ImpL3 45880   NP_476581 60
C.elegans ldh-1 174798   NP_496503 59
A.thaliana AT4G17260 827440   NP_193459 54
N.crassa NCU00720 3880705   XP_964554 37
S.pombe SPAC186.08c 2542569   NP_595026 36

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

NCI-Nature Pathway Interaction Database

BioCarta Pathways
Pathway information courtesy of BioCarta