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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. HSPA1A, heat shock 70kDa protein 1A
Sequence ID:NM_005345
RefSeqGene ID:NG_011855
Entrez Gene ID:3303
Ensembl ID:ENSG00000204389

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymphoreticular, mammary gland, muscle, nervous, pancreas, pancreatic islet, peripheral nervous system, pineal gland, placenta, pooled tissue, prostate, retina, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:6p21.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:6: 31783329 - 31785717

NM_005345 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
124273178329031785716

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3345864Full LengthBC002453heat shock 70kDa protein 1A
4123837Full LengthBC009322heat shock 70kDa protein 1A
4906865Full LengthBC018740heat shock 70kDa protein 1A

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_005336  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_005345 NP_005336   HSP70

Related Sequences

 
mRNAGenPeptSwissProt
BC002453 AAH02453 P08107
BC009322 AAH09322 P08107
BC018740 AAH18740 P08107
EU176434 ABW03885  
AB209818 BAD93055 Q59EJ3
AK291295 BAF83984 A8K5I0
AK096017 BAG53197 B3KTT5
AK294182 BAG57500 B4DFN9
AK298056 BAG60350 B4DNT8
AK301243 BAG62811 B4DVU9
AK301574 BAG63067 B4DWK5
AK303980 BAG64898 B4E1T6
AK304618 BAG65400 B4E388
AK304652 BAG65428 P08107

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens HSPA1A NP_005336 H.sapiens HSPA1B 3304 Gene Info NP_005337 100
R.norvegicus Hspa1b 294254   NP_997669 97
R.norvegicus Hspa1a 24472   NP_114177 97
M.musculus Hspa1b 15511 Gene Info NP_034608 95
M.musculus Hspa1a 193740 Gene Info NP_034609 95
D.melanogaster Hsp70Bc 48583   NP_650209 76
D.melanogaster Hsp70Bb 48582   NP_524927 76
D.melanogaster Hsp70Bbb 50022   NP_788663 76
D.melanogaster Hsp70Ba 44921   NP_731716 76
D.melanogaster Hsp70Ab 44920   NP_524798 76
A.thaliana Hsp70b 838174   NP_173055 76
D.melanogaster Hsp70Aa 48581   NP_731651 76
D.melanogaster Hsp68 42852   NP_524474 74
P.falciparum PF08_0054 2655254   XP_001349336 74

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

NCI-Nature Pathway Interaction Database

BioCarta Pathways
Pathway information courtesy of BioCarta