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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. GDNF, glial cell derived neurotrophic factor
Sequence ID:NM_000514
NM_001190468
NM_001190469
NM_199231
NM_199234
RefSeqGene ID:NG_011675
Entrez Gene ID:2668
Ensembl ID:ENSG00000168621

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
CENTRAL HYPOVENTILATION SYNDROMEASCL1
BDNF
EDN3
PHOX2B
RET
HIRSCHSPRUNG DISEASEEDN3
L1CAM
NRTN
PHOX2B
RET
HIRSCHSPRUNG DISEASE 
PHEOCHROMOCYTOMAKIF1B
MAX
RET
SDHB
SDHD
TMEM127
TMEM127
VHL

Cytogenetic Location (from UniGene)

Cytogenetic Location:5p13.1-p12Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:5: 37815826 - 37839782

 Exon Info From UCSC:
NM_000514
NM_001190468
NM_001190469
NM_199231

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
7216973Full LengthBC069119glial cell derived neurotrophic factor
7262145Full LengthBC069369glial cell derived neurotrophic factor
40112122Full LengthBC128108glial cell derived neurotrophic factor
40112125Full LengthBC128109glial cell derived neurotrophic factor

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000505  NP_954701  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000514 NP_000505 P39905 TGF_beta
NM_001190468 NP_001177397    
NM_001190469 NP_001177398    
NM_199231 NP_954701   TGF_beta

Related Sequences

 
mRNAGenPeptSwissProt
AF053748 AAD43139 P39905
BC008580 AAH08580 Q96HI3
BC069119 AAH69119 P39905
BC069369 AAH69369 P39905
BC128108 AAI28109 P39905
BC128109 AAI28110 P39905
AY052832 AAL11017 P39905
AJ001897 CAA05075 P39905
AJ001898 CAA05076 P39905
AJ001899 CAA05077 P39905
AJ001900 CAA05078 P39905
CR541923 CAG46721 P39905

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens GDNF NP_001177397 M.musculus Gdnf 14573 Gene Info NP_034405 93
R.norvegicus Gdnf 25453   NP_062012 93

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

NCI-Nature Pathway Interaction Database