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Gene Info

Gene Information For:Hs. TNF, Tumor necrosis factor
Sequence ID:NM_000594
RefSeqGene ID:NG_007462
Entrez Gene ID:7124
Ensembl ID:ENSG00000232810

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
ASTHMAADRB2
ALOX5
CCL11
HLA-G
HNMT
IL12B
IL13
MUC7
PHF11
PLA2G7
SCGB1A1
SCGB3A2
MALARIA, CEREBRALCD36
CISH
CR1
DARC
FCGR2B
GYPA
GYPC
ICAM1
NOS2
SLC4A1
TIRAP
MIGRAINEEDNRA
ESR1

Cytogenetic Location (from UniGene)

Cytogenetic Location:6p21.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:6: 31544543 - 31545312

NM_000594 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
13553154334931543703
3564013154431031544355
4024493154454331544590
45016673154489231546109

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5217636Full LengthBC028148tumor necrosis factor (TNF superfamily, member 2)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000585  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000594 NP_000585 Q5STB3
P01375
TNF

Related Sequences

 
mRNAGenPeptSwissProt
M10988 AAA61198 P01375
AF043342 AAC03542 P01375
M35592 AAC42098  
AF098751 AAF71992 P01375
BC028148 AAH28148 Q5STB3
P01375
DQ891662 ABM82588  
DQ894849 ABM85775  
FJ795028 ACO37640 C1K3N5
HQ201306 ADV31546 Q5STB3
AK314960 BAG37464 Q5STB3
AB451492 BAG70306 B5BUQ6
X01394 CAA25650 Q5STB3
P01375
AJ251878 CAB63904 Q9UBM5
AJ251879 CAB63905 Q9UBM5

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens TNF NP_000585 R.norvegicus Tnf 24835   NP_036807 80
M.musculus Tnf 21926 Gene Info NP_038721 80

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

NCI-Nature Pathway Interaction Database

BioCarta Pathways
Pathway information courtesy of BioCarta