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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. SNCA, synuclein, alpha (non A4 component of amyloid precursor)
Sequence ID:NM_000345
NM_001146054
NM_001146055
NM_007308
RefSeqGene ID:NG_011851
Entrez Gene ID:6622
Ensembl ID:ENSG00000145335

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
DEMENTIA, LEWY BODYGBA
SNCB
PARKINSON DISEASE 1 
PARKINSON DISEASE 4 

Cytogenetic Location (from UniGene)

Cytogenetic Location:4q21Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:4: 90647683 - 90758171

 Exon Info From UCSC:
NM_000345
NM_001146054
NM_001146055
NM_007308

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3604532Full LengthBC013293synuclein, alpha (non A4 component of amyloid precursor)
6147966Full LengthBC108275synuclein, alpha (non A4 component of amyloid precursor)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000336  NP_009292  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000345 NP_000336 P37840 Synuclein
NM_001146054 NP_001139526    
NM_001146055 NP_001139527    
NM_007308 NP_009292   Synuclein

Related Sequences

 
mRNAGenPeptSwissProt
L08850 AAA16117 P37840
L36675 AAA98487 P37840
L36674 AAA98493 P37840
BC013293 AAH13293 P37840
BC108275 AAI08276 P37840
AY049786 AAL15443 P37840
DQ892564 ABM83490  
EU176705 ABW03506  
HQ830267 AEG20815 F6L6N6
HQ830268 AEG20816 F6L6N6
HQ830269 AEG20817 F6L6N6
JN709859 AFA25669 H6UYS0
JN709860 AFA25670 H6UYS7
JN709861 AFA25671 H6UYS5
JN709862 AFA25672 H6UYS0
JN709863 AFA25673 H6UYS7
JN709864 AFA25674 H6UYS5
JN709865 AFA25675 H6UYS0
JN709866 AFA25676 H6UYS7
JN709867 AFA25677 H6UYS5
JN709868 AFA25678 H6UYS0
JN709869 AFA25679 H6UYS7
D31839 BAA06625 P37840
AK290169 BAF82858 P37840
CR457058 CAG33339 P37840
CR541653 CAG46454 P37840

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens SNCA NP_000336 M.musculus Snca 20617 Gene Info NP_001035916 95
R.norvegicus Snca 29219   NP_062042 95

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

NCI-Nature Pathway Interaction Database

BioCarta Pathways
Pathway information courtesy of BioCarta