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Gene Info

Gene Information For:Hs. PTGS2, Prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
Sequence ID:NM_000963
RefSeqGene ID:NG_028206
Entrez Gene ID:5743
Ensembl ID:ENSG00000073756

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:1q25.2-q25.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 186643484 - 186649422

NM_000963 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
162965186640944186643893
29663113186644380186644527
31143400186645029186645315
34013647186645598186645844
36483731186645964186646047
37323913186646780186646961
39144057186647392186647535
40584201186648189186648332
42024318186648453186648569
43194507186649370186649558

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3880850Full LengthBC013734prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000954  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000963 NP_000954 P35354 EC 1.14.99.1 EGF
An_peroxidase

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
L15326 AAA35803 P35354 EC 1.14.99.1
M90100 AAA58433 P35354 EC 1.14.99.1
BC013734 AAH13734 P35354 EC 1.14.99.1
AY151286 AAN52932 Q8IZA9  
AY462100 AAR23927 P35354 EC 1.14.99.1
EU176597 ABW03398    
EU176282 ABW03733    
HM473188 ADJ56342 D9MWI3  
AK292167 BAF84856 P35354 EC 1.14.99.1
AJ634912 CAG25548 Q6ZYK7  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PTGS2 NP_000954 M.musculus Ptgs2 19225 Gene Info NP_035328 87
R.norvegicus Ptgs2 29527   NP_058928 86

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

NCI-Nature Pathway Interaction Database

BioCarta Pathways
Pathway information courtesy of BioCarta