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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. BRCA1, breast cancer 1, early onset
Sequence ID:NM_007294
NM_007297
NM_007298
NM_007299
NM_007300
NR_027676
NM_007295
NM_007296
NM_007301
NM_007302
NM_007303
NM_007305
NM_007306
RefSeqGene ID:NG_005905
Entrez Gene ID:672
Ensembl ID:ENSG00000012048

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
BREAST CANCERAKT1
ATM
BARD1
BRCA2
BRIP1
CASP8
CDH1
CHEK2
CHEK2
HMMR
KRAS
NQO2
NQO2
PALB2
PHB
PIK3CA
PIK3CA
PPM1D
RAD51
RAD54L
RB1CC1
SLC22A18
TP53
TP53
TSG101
XRCC3
XRCC3
BREAST-OVARIAN CANCER, FAMILIAL, 1AKT1
MSH6
OPCML
PARK2
PIK3CA
PIK3CA
PANCREATIC CANCER 

Cytogenetic Location (from UniGene)

Cytogenetic Location:17q21Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:17: 41276042 - 41277381

 Exon Info From UCSC:
NM_007294
NM_007297
NM_007298
NM_007299
NM_007300

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
7961446Full LengthBC115037breast cancer 1, early onset
3686198IncompleteBC062429breast cancer 1, early onset
4342873IncompleteBC046142breast cancer 1, early onset
4804551IncompleteBC030969breast cancer 1, early onset
6042052IncompleteBC085615breast cancer 1, early onset
40017569IncompleteBC106745breast cancer 1, early onset
40017570IncompleteBC106746breast cancer 1, early onset
40017573IncompleteBC114511breast cancer 1, early onset

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_009230  NP_009229  NP_009228  NP_009225  NP_009231  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_007294 NP_009225 P38398 zf-C3HC4
BRCT
NM_007297 NP_009228   BRCT
NM_007298 NP_009229   zf-C3HC4
BRCT
NM_007299 NP_009230   zf-C3HC4
BRCT
NM_007300 NP_009231   zf-C3HC4
BRCT

Related Sequences

 
mRNAGenPeptSwissProt
U14680 AAA73985 P38398
U68041 AAB08105 Q7KYU6
AF005068 AAB61673 P38398
U64805 AAC00049 P38398
BC030969 AAH30969 Q05BZ9
BC062429 AAH62429 Q6P671
BC072418 AAH72418 P38398
BC085615 AAH85615 Q5U3B7
BC106745 AAI06746 Q3B891
BC106746 AAI06747 Q3B890
BC115037 AAI15038 Q1RMC1
AY354539 AAQ92977 Q5YLB2
AY751490 AAU93634 Q5XLT4
DQ333386 ABC59810 C6YB45
DQ333387 ABC59811 C6YB46
DQ363751 ABC88652 C6YB47
JN686490 AEQ98814 G8I0D8
AK293762 BAG57181 B4DES0
AK316200 BAH14571 B7ZA85

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens BRCA1 NP_009225 M.musculus Brca1 12189 Gene Info NP_033894 58
R.norvegicus Brca1 497672   NP_036646 58

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

NCI-Nature Pathway Interaction Database

BioCarta Pathways
Pathway information courtesy of BioCarta