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Gene Info

Gene Information For:Hs. EDN3, endothelin 3
Sequence ID:NM_000114
NM_207032
NM_207033
NM_207034
RefSeqGene ID:NG_008050
Entrez Gene ID:1908
Ensembl ID:ENSG00000124205

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
CENTRAL HYPOVENTILATION SYNDROMEASCL1
BDNF
GDNF
PHOX2B
RET
HIRSCHSPRUNG DISEASEGDNF
L1CAM
NRTN
PHOX2B
RET
HIRSCHSPRUNG DISEASE 
WAARDENBURG SYNDROME, TYPE 4AEDNRB
SOX10
WAARDENBURG SYNDROME, TYPE 4B 

Cytogenetic Location (from UniGene)

Cytogenetic Location:20q13.2-q13.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:20: 57875481 - 57901047

 Exon Info From UCSC:
NM_000114
NM_207032
NM_207033
NM_207034

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4139312Full LengthBC008876endothelin 3
5202210Full LengthBC053866endothelin 3

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000105  NP_996917  NP_996915  NP_996916  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000114 NP_000105 P14138 Endothelin
NM_207032 NP_996915   Endothelin
NM_207033 NP_996916   Endothelin
NM_207034 NP_996917 P14138 Endothelin

Related Sequences

 
mRNAGenPeptSwissProt
J05081 AAA52405 P14138
BC008876 AAH08876 P14138
BC053866 AAH53866 P14138
BT007085 AAP35748 P14138
DQ096281 AAZ03610 Q4FAT2
HQ447100 ADQ31587  
X52001 CAA36252 P14138

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens EDN3 NP_000105 M.musculus Edn3 13616 Gene Info NP_031929 69
R.norvegicus Edn3 366270   NP_001071118 63

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

NCI-Nature Pathway Interaction Database