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Gene Info

Gene Information For:Hs. GCK, Glucokinase (hexokinase 4)
Sequence ID:NM_000162
NM_033508
NM_033507
RefSeqGene ID:NG_008847
Entrez Gene ID:2645
Ensembl ID:ENSG00000106633

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
DIABETES MELLITUS, GESTATIONAL 
DIABETES MELLITUS, NON-INSULIN-DEPENDENTABCC8
AKT2
CDKAL1
ENPP1
GCGR
GPD2
HMGA1
HMGA1
HNF1A
HNF1B
HNF4A
IGF2BP2
IL6
IRS1
IRS2
KCNJ11
LIPC
MAPK8IP1
MTNR1B
NEUROD1
NEUROD1
NEUROD1
PAX4
PDX1
PPARG
PTPN1
RETN
SLC2A4
SLC30A8
TCF7L2
VEGFA
WFS1
WFS1
DIABETES MELLITUS, PERMANENT NEONATALABCC8
INS
KCNJ11
HYPERINSULINEMIC HYPOGLYCEMIA, FAMILIAL, 3 

Cytogenetic Location (from UniGene)

Cytogenetic Location:7p15.3-p15.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:7: 44183876 - 44198881

 Exon Info From UCSC:
NM_000162
NM_033508
NM_033507

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3536582Full LengthBC001890glucokinase (hexokinase 4)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_277043  NP_000153  NP_277042  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000162 NP_000153 Q53Y25
P35557
EC 2.7.1.2 Hexokinase_1
Hexokinase_2
NM_033507 NP_277042     Hexokinase_1
Hexokinase_2
NM_033508 NP_277043     Hexokinase_1
Hexokinase_2

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M88011 AAA51824 Q53Y25
P35557
EC 2.7.1.2
M90299 AAA52562 Q53Y25
P35557
EC 2.7.1.2
M69051 AAB59563 P35557 EC 2.7.1.2
BC001890 AAH01890 Q53Y25
P35557
EC 2.7.1.2
BT007062 AAP35711 Q53Y25
P35557
EC 2.7.1.2
DQ893835 ABM84761    
EU008605 ABS31137 A7LFL1  
AK122876 BAG53774 P35557 EC 2.7.1.2

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens GCK NP_000153 M.musculus Gck 103988 Gene Info NP_034422 96
R.norvegicus Gck 24385   NP_036697 95
D.melanogaster Hex-C 44008   NP_524674 47
A.thaliana HXK3 841200   NP_175220 37

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

NCI-Nature Pathway Interaction Database