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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. IL1B, interleukin 1, beta
Sequence ID:NM_000576
RefSeqGene ID:NG_008851
Entrez Gene ID:3553
Ensembl ID:ENSG00000125538

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
GASTRIC CANCER RISK AFTER H. PYLORI INFECTIONAPC
APC
CASP10
CDH1
ERBB2
FGFR2
IL1RN
IRF1
KLF6
KLF6
KRAS
MUTYH
PIK3CA
PIK3CA

Cytogenetic Location (from UniGene)

Cytogenetic Location:2q14Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 113587937 - 113590356

NM_000576 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
1814113587336113588149
815945113588868113588998
9461110113590238113590402
11111312113590950113591151
13131364113593142113593193
13651426113593759113593820
14271498113594284113594355

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3875593Full LengthBC008678interleukin 1, beta

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000567  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000576 NP_000567 P01584 IL1
IL1_propep

Related Sequences

 
mRNAGenPeptSwissProt
K02770 AAA36106 P01584
M15330 AAA59135 P01584
M54933 AAA59136 P01584
AF043335 AAC03536 O43645
BC008678 AAH08678 P01584
BT007213 AAP35877 P01584
DQ890673 ABM81599  
DQ893854 ABM84780  
AB451494 BAG70308 B5BUQ8
X02532 CAA26372 P01584
X56087 CAA39567 P01584
CR407679 CAG28607 P01584

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens IL1B NP_000567 M.musculus Il1b 16176 Gene Info NP_032387 70
R.norvegicus Il1b 24494   NP_113700 68

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

NCI-Nature Pathway Interaction Database

BioCarta Pathways
Pathway information courtesy of BioCarta